EC number:3.6.1.5

Enzyme

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     3. Hydrolases
        3.6 Acting on acid anhydrides
            3.6.1 In phosphorus-containing anhydrides
ID:3.6.1.5
Description:Apyrase.
Alternative Name: ATP-diphosphohydrolase.
ATP-diphosphatase.
ADPase.
Adenosine diphosphatase.
Prosite: PDOC00952;
PDB:
PDBScop
4KH6
4KH5
4KH4
4JEP
4CD3
 » show all
Cath: 3.30.420.150; 3.30.420.40; 3.40.50.720; 3.90.176.10; 1.20.82.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 3.6.1.5
BRENDA Enzyme Link: BRENDA 3.6.1.5
KEGG Enzyme Link: KEGG3.6.1.5
BioCyc Enzyme Link: BioCyc 3.6.1.5
ExPASy Enzyme Link: ExPASy3.6.1.5
EC2PDB Enzyme Link: EC2PDB 3.6.1.5
ExplorEnz Enzyme Link: ExplorEnz 3.6.1.5
PRIAM enzyme-specific profiles Link: PRIAM 3.6.1.5
IntEnz Enzyme Link: IntEnz 3.6.1.5
MEDLINE Enzyme Link: MEDLINE 3.6.1.5

EC number:3.6.1.5

MSA:

3.6.1.5;
Phylogenetic Tree:

3.6.1.5;
Uniprot:
M-CSA:
RHEA:36795 a ribonucleoside 5'-triphosphate + 2 H2O = a ribonucleoside 5'-phosphate + 2 H(+) + 2 phosphate
RULE(radius=1) [*:1]=[P;H0;+0:2](-[*:3])(-[O;H0;+0:4]-[*:5])-[O;H0;+0:6]-[P;H0;+0:7](=[*:8])(-[*:9])-[*:10].[OH2;+0:11].[OH2;+0:12]>>[*:5]-[OH;+0:4].[*:8]=[P;H0;+0:7](-[*:9])(-[*:10])-[OH;+0:12].[*:1]=[P;H0;+0:2](-[*:3])(-[OH;+0:6])-[OH;+0:11]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Gene ytkD of Bacillus subtilis encodes an atypical nucleoside triphosphatase member of the Nudix hydrolase superfamily.Xu W, Jones CR, Dunn CA, Bessman MJ2004 Dec15576788
YND1, a homologue of GDA1, encodes membrane-bound apyrase required for Golgi N- and O-glycosylation in Saccharomyces cerevisiae.Gao XD, Kaigorodov V, Jigami Y1999 Jul 2310409709