EC number:3.6.1.53
Enzyme
Download| EC Tree |
| 3. Hydrolases |
| 3.6 Acting on acid anhydrides |
| 3.6.1 In phosphorus-containing anhydrides |
| ID: | 3.6.1.53 |
|---|---|
| Description: | Mn(2+)-dependent ADP-ribose/CDP-alcohol diphosphatase. |
| Alternative Name: |
Mn(2+)-dependent ADP-ribose/CDP-alcohol pyrophosphatase. ADPRibase-Mn. |
| Cath: | 3.60.21.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.6.1.53 |
| BRENDA Enzyme Link: | BRENDA 3.6.1.53 |
| KEGG Enzyme Link: | KEGG3.6.1.53 |
| BioCyc Enzyme Link: | BioCyc 3.6.1.53 |
| ExPASy Enzyme Link: | ExPASy3.6.1.53 |
| EC2PDB Enzyme Link: | EC2PDB 3.6.1.53 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.6.1.53 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.6.1.53 |
| IntEnz Enzyme Link: | IntEnz 3.6.1.53 |
| MEDLINE Enzyme Link: | MEDLINE 3.6.1.53 |
| RHEA:32487 | CDP-choline + H2O = CMP + 2 H(+) + phosphocholine |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[OH2;+0:7]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[OH;+0:7] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Rat liver nucleoside diphosphosugar or diphosphoalcohol pyrophosphatases different from nucleotide pyrophosphatase or phosphodiesterase I: substrate specificities of Mg(2+)-and/or Mn(2+)-dependent hydrolases acting on ADP-ribose. | Canales J, Pinto RM, Costas MJ, Hernández MT, Miró A, Bernet D, Fernández A, Cameselle JC | 1995 Jan 19 | 7819284 |
| Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase: a novel metallophosphoesterase family preferentially expressed in rodent immune cells. | Canales J, Fernández A, Ribeiro JM, Cabezas A, Rodrigues JR, Cameselle JC, Costas MJ | 2008 Jul 1 | 18352857 |
| RHEA:10412 | ADP-D-ribose + H2O = AMP + D-ribose 5-phosphate + 2 H(+) |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[OH2;+0:7]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[OH;+0:7] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Rat liver nucleoside diphosphosugar or diphosphoalcohol pyrophosphatases different from nucleotide pyrophosphatase or phosphodiesterase I: substrate specificities of Mg(2+)-and/or Mn(2+)-dependent hydrolases acting on ADP-ribose. | Canales J, Pinto RM, Costas MJ, Hernández MT, Miró A, Bernet D, Fernández A, Cameselle JC | 1995 Jan 19 | 7819284 |
| Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase: a novel metallophosphoesterase family preferentially expressed in rodent immune cells. | Canales J, Fernández A, Ribeiro JM, Cabezas A, Rodrigues JR, Cameselle JC, Costas MJ | 2008 Jul 1 | 18352857 |