EC number:3.7.1.19
| ID: | 3.7.1.19 |
|---|---|
| Description: | 2,6-dihydroxypseudooxynicotine hydrolase. |
| Cath: | 1.20.1440.110; 3.40.50.1820; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.7.1.19 |
| BRENDA Enzyme Link: | BRENDA 3.7.1.19 |
| KEGG Enzyme Link: | KEGG3.7.1.19 |
| BioCyc Enzyme Link: | BioCyc 3.7.1.19 |
| ExPASy Enzyme Link: | ExPASy3.7.1.19 |
| EC2PDB Enzyme Link: | EC2PDB 3.7.1.19 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.7.1.19 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.7.1.19 |
| IntEnz Enzyme Link: | IntEnz 3.7.1.19 |
| MEDLINE Enzyme Link: | MEDLINE 3.7.1.19 |
| RHEA:34167 | 2,6-dihydroxypseudooxynicotine + H2O = 2,6-dihydroxypyridine + 4-(methylamino)butanoate + H(+) |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[*:3])-[c;H0;+0:4](:[*:5]):[*:6].[OH2;+0:7]>>[*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:7].[*:5]:[cH;+0:4]:[*:6] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The bacterial oxidation of nicotine. VI. The metabolism of 2,6-dihydroxypseudooxynicotine. | Gherna RL, Richardson SH, Rittenberg SC | 1965 Sep | 5835946 |
| Structure and action of a C-C bond cleaving alpha/beta-hydrolase involved in nicotine degradation. | Schleberger C, Sachelaru P, Brandsch R, Schulz GE | 2007 Mar 23 | 17275835 |
| An alpha/beta-fold C--C bond hydrolase is involved in a central step of nicotine catabolism by Arthrobacter nicotinovorans. | Sachelaru P, Schiltz E, Igloi GL, Brandsch R | 2005 Dec | 16321959 |