Enzyme

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EC Tree
     3. Hydrolases
        3.7 Acting on carbon-carbon bonds
            3.7.1 In ketonic substances
ID:3.7.1.23
Description:Maleylpyruvate hydrolase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.7.1.23
BRENDA Enzyme Link: BRENDA 3.7.1.23
KEGG Enzyme Link: KEGG3.7.1.23
BioCyc Enzyme Link: BioCyc 3.7.1.23
ExPASy Enzyme Link: ExPASy3.7.1.23
EC2PDB Enzyme Link: EC2PDB 3.7.1.23
ExplorEnz Enzyme Link: ExplorEnz 3.7.1.23
PRIAM enzyme-specific profiles Link: PRIAM 3.7.1.23
IntEnz Enzyme Link: IntEnz 3.7.1.23
MEDLINE Enzyme Link: MEDLINE 3.7.1.23
MSA:

3.7.1.23;

Phylogenetic Tree:

3.7.1.23;

Uniprot:
M-CSA:
RHEA:47956 3-maleylpyruvate + H2O = H(+) + maleate + pyruvate
RULE(radius=1) [*:1]-[C;H0;+0:2](=[*:3])-[CH2;+0:4]-[*:5].[OH2;+0:6]>>[*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:6].[*:5]-[CH3;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The enzymic degradation of alkyl-substituted gentisates, maleates and malates.Hopper DJ, Chapman PJ, Dagley S1971 Mar5124802
HbzF catalyzes direct hydrolysis of maleylpyruvate in the gentisate pathway of Pseudomonas alcaligenes NCIMB 9867.Liu K, Liu TT, Zhou NY2013 Feb23204427
Purification and some properties of maleylpyruvate hydrolase and fumarylpyruvate hydrolase from Pseudomonas alcaligenes.Bayly RC, Chapman PJ, Dagley S, Di Berardino D1980 Jul7400101