EC number:3.7.1.3

Enzyme

Download
EC Tree
     3. Hydrolases
        3.7 Acting on carbon-carbon bonds
            3.7.1 In ketonic substances
ID:3.7.1.3
Description:Kynureninase.
Alternative Name: L-kynurenine hydrolase.
Cath: 3.40.640.10; 3.90.1150.10;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 3.7.1.3
BRENDA Enzyme Link: BRENDA 3.7.1.3
KEGG Enzyme Link: KEGG3.7.1.3
BioCyc Enzyme Link: BioCyc 3.7.1.3
ExPASy Enzyme Link: ExPASy3.7.1.3
EC2PDB Enzyme Link: EC2PDB 3.7.1.3
ExplorEnz Enzyme Link: ExplorEnz 3.7.1.3
PRIAM enzyme-specific profiles Link: PRIAM 3.7.1.3
IntEnz Enzyme Link: IntEnz 3.7.1.3
MEDLINE Enzyme Link: MEDLINE 3.7.1.3

EC number:3.7.1.3

MSA:

3.7.1.3;
Phylogenetic Tree:

3.7.1.3;
Uniprot:
M-CSA:
RHEA:25143 3-hydroxy-L-kynurenine + H2O = 3-hydroxyanthranilate + H(+) + L-alanine
RULE(radius=1) [*:1]-[CH2;+0:2]-[C;H0;+0:3](=[*:4])-[*:5].[OH2;+0:6]>>[*:1]-[CH3;+0:2].[*:4]=[C;H0;+0:3](-[*:5])-[OH;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Crystal structure of Homo sapiens kynureninase.Lima S, Khristoforov R, Momany C, Phillips RS2007 Mar 1317300176
RHEA:16813 H2O + L-kynurenine = anthranilate + H(+) + L-alanine
RULE(radius=1) [*:1]-[CH2;+0:2]-[C;H0;+0:3](=[*:4])-[*:5].[OH2;+0:6]>>[*:1]-[CH3;+0:2].[*:4]=[C;H0;+0:3](-[*:5])-[OH;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Three-dimensional structure of kynureninase from Pseudomonas fluorescens.Momany C, Levdikov V, Blagova L, Lima S, Phillips RS2004 Feb 1014756555