EC number:3.7.1.8

Enzyme

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EC Tree
     3. Hydrolases
        3.7 Acting on carbon-carbon bonds
            3.7.1 In ketonic substances
ID:3.7.1.8
Description:2,6-dioxo-6-phenylhexa-3-enoate hydrolase.
Alternative Name: HOHPDA hydrolase.
Cath: 3.40.50.1820;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 3.7.1.8
BRENDA Enzyme Link: BRENDA 3.7.1.8
KEGG Enzyme Link: KEGG3.7.1.8
BioCyc Enzyme Link: BioCyc 3.7.1.8
ExPASy Enzyme Link: ExPASy3.7.1.8
EC2PDB Enzyme Link: EC2PDB 3.7.1.8
ExplorEnz Enzyme Link: ExplorEnz 3.7.1.8
PRIAM enzyme-specific profiles Link: PRIAM 3.7.1.8
IntEnz Enzyme Link: IntEnz 3.7.1.8
MEDLINE Enzyme Link: MEDLINE 3.7.1.8

EC number:3.7.1.8

MSA:

3.7.1.8;
Phylogenetic Tree:

3.7.1.8;
Uniprot:
M-CSA:
RHEA:42468 2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoate + H2O = 2-oxopent-4-enoate + salicylate
RULE(radius=1) [*:1]=[C;H0;+0:2](-[*:3])-[CH;+0:4]=[*:5]-[CH;+0:6]=[C;H0;+0:7](-[*:8])-[OH;+0:9].[OH2;+0:10]>>[*:8]-[C;H0;+0:7](=[O;H0;+0:9])-[CH2;+0:6]-[*:5]=[CH2;+0:4].[*:1]=[C;H0;+0:2](-[*:3])-[OH;+0:10]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction
RHEA:17161 2,6-dioxo-6-phenylhexa-3-enoate + H2O = 2-oxopent-4-enoate + benzoate + H(+)
RULE(radius=1) [*:1]=[C;H0;+0:2](-[*:3])-[CH2;+0:4]-[CH;+0:5]=[CH;+0:6]-[*:7].[OH2;+0:8]>>[*:7]-[CH2;+0:6]-[CH;+0:5]=[CH2;+0:4].[*:1]=[C;H0;+0:2](-[*:3])-[OH;+0:8]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction