EC number:3.8.1.2
| ID: | 3.8.1.2 |
|---|---|
| Description: | (S)-2-haloacid dehalogenase. |
| Alternative Name: |
L-DEX. L-2-haloacid dehalogenase. Halocarboxylic acid halidohydrolase. DL-2-haloacid dehalogenase. 2-halocarboxylic acid dehalogenase II. 2-haloalkanoid acid halidohydrolase. 2-haloalkanoic acid dehalogenase. 2-haloacid halidohydrolase. 2-haloacid dehalogenase. |
| Cath: | 1.10.150.240; 3.40.50.1000; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.8.1.2 |
| BRENDA Enzyme Link: | BRENDA 3.8.1.2 |
| KEGG Enzyme Link: | KEGG3.8.1.2 |
| BioCyc Enzyme Link: | BioCyc 3.8.1.2 |
| ExPASy Enzyme Link: | ExPASy3.8.1.2 |
| EC2PDB Enzyme Link: | EC2PDB 3.8.1.2 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.8.1.2 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.8.1.2 |
| IntEnz Enzyme Link: | IntEnz 3.8.1.2 |
| MEDLINE Enzyme Link: | MEDLINE 3.8.1.2 |
| RHEA:11192 | an (S)-2-haloacid + H2O = a (2R)-2-hydroxycarboxylate + a halide anion + H(+) |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[*;H0;+0:4].[OH2;+0:5]>>[*-;H0:4].[*:1]-[CH;+0:2](-[*:3])-[OH;+0:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Cloning, sequencing and expression in Escherichia coli of two Rhizobium sp. genes encoding haloalkanoate dehalogenases of opposite stereospecificity. | Cairns SS, Cornish A, Cooper RA | 1996 Feb 1 | 8654424 |
| Improved catalytic performance of a 2-haloacid dehalogenase from Azotobacter sp. by ion-exchange immobilisation. | Diez A, Prieto MI, Alvarez MJ, Bautista JM, Garrido J, Puyet A | 1996 Mar 27 | 8607850 |
| Purification and characterization of thermostable and nonthermostable 2-haloacid dehalogenases with different stereospecificities from Pseudomonas sp. strain YL. | Liu JQ, Kurihara T, Hasan AK, Nardi-Dei V, Koshikawa H, Esaki N, Soda K | 1994 Jul | 8074519 |
| Stereospecificity of 2-monochloropropionate dehalogenation by the two dehalogenases of Pseudomonas putida PP3: evidence for two different dehalogenation mechanisms. | Weightman AJ, Weightman AL, Slater JH | 1982 Aug | 7142958 |
| Bacterial assimilation of D- and L-2-chloropropionates and occurrence of a new dehalogenase. | Motosugi K, Esaki N, Soda K | 1982 May | 7103659 |
| Purification and properties of a new enzyme, DL-2-haloacid dehalogenase, from Pseudomonas sp. | Motosugi K, Esaki N, Soda K | 1982 May | 7068529 |
| 2-Haloacid dehalogenase from a 4-chlorobenzoate-degrading Pseudomonas spec. CBS 3. | Klages U, Krauss S, Lingens F | 1983 May | 6873881 |
| Purification and characterization of 2-halocarboxylic acid dehalogenase II from Pseudomonas spec. CBS 3. | Mörsberger FM, Müller R, Otto MK, Lingens F, Kulbe KD | 1991 Oct | 1772590 |