EC number:3.8.1.5
| ID: | 3.8.1.5 |
|---|---|
| Description: | Haloalkane dehalogenase. |
| Alternative Name: |
1-chlorohexane halidohydrolase. |
| Cath: | 3.40.50.1820; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.8.1.5 |
| BRENDA Enzyme Link: | BRENDA 3.8.1.5 |
| KEGG Enzyme Link: | KEGG3.8.1.5 |
| BioCyc Enzyme Link: | BioCyc 3.8.1.5 |
| ExPASy Enzyme Link: | ExPASy3.8.1.5 |
| EC2PDB Enzyme Link: | EC2PDB 3.8.1.5 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.8.1.5 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.8.1.5 |
| IntEnz Enzyme Link: | IntEnz 3.8.1.5 |
| MEDLINE Enzyme Link: | MEDLINE 3.8.1.5 |
| RHEA:25185 | 1,2-dichloroethane + H2O = 2-chloroethanol + chloride + H(+) |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[Cl;H0;+0:3].[OH2;+0:4]>>[*:1]-[CH2;+0:2]-[OH;+0:4].[Cl-;H0:3] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and characterization of hydrolytic haloalkane dehalogenase from Xanthobacter autotrophicus GJ10. | Keuning S, Janssen DB, Witholt B | 1985 Aug | 4019411 |
| Characterization of 1-chlorohexane halidohydrolase, a dehalogenase of wide substrate range from an Arthrobacter sp. | Scholtz R, Leisinger T, Suter F, Cook AM | 1987 Nov | 3667524 |
| Purification and properties of haloalkane dehalogenase from Corynebacterium sp. strain m15-3. | Yokota T, Omori T, Kodama T | 1987 Sep | 3624201 |
| RHEA:19081 | 1-haloalkane + H2O = a halide anion + a primary alcohol + H(+) |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[*;H0;+0:3].[OH2;+0:4]>>[*-;H0:3].[*:1]-[CH2;+0:2]-[OH;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Degradation of 1,3-dichloropropene by pseudomonas cichorii 170. | Poelarends GJ, Wilkens M, Larkin MJ, van Elsas JD, Janssen DB | 1998 Aug | 9687453 |
| Crystallographic analysis of the catalytic mechanism of haloalkane dehalogenase. | Verschueren KH, Seljée F, Rozeboom HJ, Kalk KH, Dijkstra BW | 1993 Jun 24 | 8515812 |
| Replacement of tryptophan residues in haloalkane dehalogenase reduces halide binding and catalytic activity. | Kennes C, Pries F, Krooshof GH, Bokma E, Kingma J, Janssen DB | 1995 Mar 1 | 7705355 |
| Purification and characterization of hydrolytic haloalkane dehalogenase from Xanthobacter autotrophicus GJ10. | Keuning S, Janssen DB, Witholt B | 1985 Aug | 4019411 |
| Characterization of 1-chlorohexane halidohydrolase, a dehalogenase of wide substrate range from an Arthrobacter sp. | Scholtz R, Leisinger T, Suter F, Cook AM | 1987 Nov | 3667524 |
| Purification and properties of haloalkane dehalogenase from Corynebacterium sp. strain m15-3. | Yokota T, Omori T, Kodama T | 1987 Sep | 3624201 |