Enzyme

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     3. Hydrolases
        3.8 Acting on halide bonds
            3.8.1 In carbon-halide compounds
ID:3.8.1.6
Description:4-chlorobenzoate dehalogenase.
Prosite: PDOC00150;
PDB:
PDBScop
5ZAI 8059901; 8059902; 8059901; 8059902; 8059901; 8059902; 8059901; 8059902; 8059901; 8059902; 8059901; 8059902;
2HW5 8059897; 8059898; 8059897; 8059898; 8059897; 8059898; 8059897; 8059898; 8059897; 8059898; 8059897; 8059898;
3Q0J 8059895; 8059896; 8059895; 8059896; 8059895; 8059896; 8059895; 8059896; 8059895; 8059896; 8059895; 8059896;
3Q0G 8059895; 8059896; 8059895; 8059896; 8059895; 8059896; 8059895; 8059896; 8059895; 8059896; 8059895; 8059896;
4FJW 8059895; 8059896; 8059895; 8059896; 8059895; 8059896;
 » show all

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.8.1.6
BRENDA Enzyme Link: BRENDA 3.8.1.6
KEGG Enzyme Link: KEGG3.8.1.6
BioCyc Enzyme Link: BioCyc 3.8.1.6
ExPASy Enzyme Link: ExPASy3.8.1.6
EC2PDB Enzyme Link: EC2PDB 3.8.1.6
ExplorEnz Enzyme Link: ExplorEnz 3.8.1.6
PRIAM enzyme-specific profiles Link: PRIAM 3.8.1.6
IntEnz Enzyme Link: IntEnz 3.8.1.6
MEDLINE Enzyme Link: MEDLINE 3.8.1.6
MSA:

3.8.1.6;

Phylogenetic Tree:

3.8.1.6;

Uniprot:
M-CSA:
RHEA:23440 4-chlorobenzoate + H2O = 4-hydroxybenzoate + chloride + H(+)
RULE(radius=1) [*:1]:[c;H0;+0:2](:[*:3])-[Cl;H0;+0:4].[OH2;+0:5]>>[*:1]:[c;H0;+0:2](:[*:3])-[OH;+0:5].[Cl-;H0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Incorporation of [18O]water into 4-hydroxybenzoic acid in the reaction of 4-chlorobenzoate dehalogenase from pseudomonas spec. CBS 3.Müller R, Thiele J, Klages U, Lingens F1984 Oct 156497878
Enzymatic dehalogenation of certain brominated and chlorinated compounds.HEPPEL LA, PORTERFIELD VT1948 Nov18889931