Enzyme

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EC Tree
     3. Hydrolases
        3.8 Acting on halide bonds
            3.8.1 In carbon-halide compounds
ID:3.8.1.7
Description:4-chlorobenzoyl-CoA dehalogenase.
Cath: 1.10.12.10; 3.90.226.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.8.1.7
BRENDA Enzyme Link: BRENDA 3.8.1.7
KEGG Enzyme Link: KEGG3.8.1.7
BioCyc Enzyme Link: BioCyc 3.8.1.7
ExPASy Enzyme Link: ExPASy3.8.1.7
EC2PDB Enzyme Link: EC2PDB 3.8.1.7
ExplorEnz Enzyme Link: ExplorEnz 3.8.1.7
PRIAM enzyme-specific profiles Link: PRIAM 3.8.1.7
IntEnz Enzyme Link: IntEnz 3.8.1.7
MEDLINE Enzyme Link: MEDLINE 3.8.1.7
MSA:

3.8.1.7;

Phylogenetic Tree:

3.8.1.7;

Uniprot:
M-CSA:
RHEA:14853 4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl-CoA + chloride + H(+)
RULE(radius=1) [*:1]:[c;H0;+0:2](:[*:3])-[Cl;H0;+0:4].[OH2;+0:5]>>[*:1]:[c;H0;+0:2](:[*:3])-[OH;+0:5].[Cl-;H0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Purification and characterization of 4-chlorobenzoyl CoA dehalogenase from Arthrobacter sp. strain 4-CB1.Crooks GP, Copley SD1994 Sep 277918379
Dehalogenation of 4-chlorobenzoate. Characterisation of 4-chlorobenzoyl-coenzyme A dehalogenase from Pseudomonas sp. CBS3.Löffler F, Lingens F, Müller R1995 Sep7579994
Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3.Chang KH, Liang PH, Beck W, Scholten JD, Dunaway-Mariano D1992 Jun 231610806
The purification and characterisation of 4-chlorobenzoate:CoA ligase and 4-chlorobenzoyl CoA dehalogenase from Arthrobacter sp. strain TM-1.Zhou L, Marks TS, Poh RP, Smith RJ, Chowdhry BZ, Smith AR2004 Apr15068371