EC number:4.1.1.102
| ID: | 4.1.1.102 |
|---|---|
| Description: | Phenacrylate decarboxylase. |
| Alternative Name: |
Ferulic acid decarboxylase. |
| Cath: | 1.20.5.4570; 3.40.50.1950; |
3D structure
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Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 4.1.1.102 |
| BRENDA Enzyme Link: | BRENDA 4.1.1.102 |
| KEGG Enzyme Link: | KEGG4.1.1.102 |
| BioCyc Enzyme Link: | BioCyc 4.1.1.102 |
| ExPASy Enzyme Link: | ExPASy4.1.1.102 |
| EC2PDB Enzyme Link: | EC2PDB 4.1.1.102 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.1.1.102 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.1.1.102 |
| IntEnz Enzyme Link: | IntEnz 4.1.1.102 |
| MEDLINE Enzyme Link: | MEDLINE 4.1.1.102 |
EC number:4.1.1.102
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:46920 | H(+) + trans-cinnamate = CO2 + styrene |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[OH;+0:3])-[CH;+0:4]=[*:5].[H+;H0:6]>>[*:1]=[C;H0;+0:2]=[O;H0;+0:3].[*:5]=[CH2;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| UbiX is a flavin prenyltransferase required for bacterial ubiquinone biosynthesis. | White MD, Payne KA, Fisher K, Marshall SA, Parker D, Rattray NJ, Trivedi DK, Goodacre R, Rigby SE, Scrutton NS, Hay S, Leys D | 2015 Jun 25 | 26083743 |
| New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition. | Payne KA, White MD, Fisher K, Khara B, Bailey SS, Parker D, Rattray NJ, Trivedi DK, Goodacre R, Beveridge R, Barran P, Rigby SE, Scrutton NS, Hay S, Leys D | 2015 Jun 25 | 26083754 |
| Structure and Mechanism of Ferulic Acid Decarboxylase (FDC1) from Saccharomyces cerevisiae. | Bhuiya MW, Lee SG, Jez JM, Yu O | 2015 Jun 15 | 25862228 |
| Isofunctional enzymes PAD1 and UbiX catalyze formation of a novel cofactor required by ferulic acid decarboxylase and 4-hydroxy-3-polyprenylbenzoic acid decarboxylase. | Lin F, Ferguson KL, Boyer DR, Lin XN, Marsh EN | 2015 Apr 17 | 25647642 |
| PAD1 and FDC1 are essential for the decarboxylation of phenylacrylic acids in Saccharomyces cerevisiae. | Mukai N, Masaki K, Fujii T, Kawamukai M, Iefuji H | 2010 Jun | 20471595 |
| RHEA:33807 | H(+) + trans-ferulate = 2-methoxy-4-vinylphenol + CO2 |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[OH;+0:3])-[CH;+0:4]=[*:5].[H+;H0:6]>>[*:1]=[C;H0;+0:2]=[O;H0;+0:3].[*:5]=[CH2;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Gene cloning, transcriptional analysis, purification, and characterization of phenolic acid decarboxylase from Bacillus subtilis. | Cavin JF, Dartois V, Diviès C | 1998 Apr | 9546183 |
| New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition. | Payne KA, White MD, Fisher K, Khara B, Bailey SS, Parker D, Rattray NJ, Trivedi DK, Goodacre R, Beveridge R, Barran P, Rigby SE, Scrutton NS, Hay S, Leys D | 2015 Jun 25 | 26083754 |
| Structure and Mechanism of Ferulic Acid Decarboxylase (FDC1) from Saccharomyces cerevisiae. | Bhuiya MW, Lee SG, Jez JM, Yu O | 2015 Jun 15 | 25862228 |
| Isofunctional enzymes PAD1 and UbiX catalyze formation of a novel cofactor required by ferulic acid decarboxylase and 4-hydroxy-3-polyprenylbenzoic acid decarboxylase. | Lin F, Ferguson KL, Boyer DR, Lin XN, Marsh EN | 2015 Apr 17 | 25647642 |
| PAD1 and FDC1 are essential for the decarboxylation of phenylacrylic acids in Saccharomyces cerevisiae. | Mukai N, Masaki K, Fujii T, Kawamukai M, Iefuji H | 2010 Jun | 20471595 |
| RHEA:33227 | H(+) + trans-4-coumarate = 4-hydroxystyrene + CO2 |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[OH;+0:3])-[CH;+0:4]=[*:5].[H+;H0:6]>>[*:1]=[C;H0;+0:2]=[O;H0;+0:3].[*:5]=[CH2;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition. | Payne KA, White MD, Fisher K, Khara B, Bailey SS, Parker D, Rattray NJ, Trivedi DK, Goodacre R, Beveridge R, Barran P, Rigby SE, Scrutton NS, Hay S, Leys D | 2015 Jun 25 | 26083754 |
| Structure and Mechanism of Ferulic Acid Decarboxylase (FDC1) from Saccharomyces cerevisiae. | Bhuiya MW, Lee SG, Jez JM, Yu O | 2015 Jun 15 | 25862228 |
| Isofunctional enzymes PAD1 and UbiX catalyze formation of a novel cofactor required by ferulic acid decarboxylase and 4-hydroxy-3-polyprenylbenzoic acid decarboxylase. | Lin F, Ferguson KL, Boyer DR, Lin XN, Marsh EN | 2015 Apr 17 | 25647642 |
| PAD1 and FDC1 are essential for the decarboxylation of phenylacrylic acids in Saccharomyces cerevisiae. | Mukai N, Masaki K, Fujii T, Kawamukai M, Iefuji H | 2010 Jun | 20471595 |