EC number:4.1.1.110

Enzyme

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EC Tree
     4. Lyases
        4.1 Carbon-carbon lyases
            4.1.1 Carboxy-lyases
ID:4.1.1.110
Description:Bisphosphomevalonate decarboxylase.
Alternative Name: Mevalonate 3,5-bisphosphate decarboxylase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.1.1.110
BRENDA Enzyme Link: BRENDA 4.1.1.110
KEGG Enzyme Link: KEGG4.1.1.110
BioCyc Enzyme Link: BioCyc 4.1.1.110
ExPASy Enzyme Link: ExPASy4.1.1.110
EC2PDB Enzyme Link: EC2PDB 4.1.1.110
ExplorEnz Enzyme Link: ExplorEnz 4.1.1.110
PRIAM enzyme-specific profiles Link: PRIAM 4.1.1.110
IntEnz Enzyme Link: IntEnz 4.1.1.110
MEDLINE Enzyme Link: MEDLINE 4.1.1.110

EC number:4.1.1.110

MSA:

4.1.1.110;
Phylogenetic Tree:

4.1.1.110;
Uniprot:
M-CSA:
RHEA:56500 (R)-3,5-bisphosphomevalonate + H(+) = CO2 + isopentenyl phosphate + phosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3])(-[CH2;+0:4]-[C;H0;+0:5](=[*:6])-[OH;+0:7])-[O;H0;+0:8]-[*:9].[H+;H0:10]>>[*:1]-[C;H0;+0:2](-[*:3])=[CH2;+0:4].[*:9]-[OH;+0:8].[*:6]=[C;H0;+0:5]=[O;H0;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
An Adaptation To Life In Acid Through A Novel Mevalonate Pathway.Vinokur JM, Cummins MC, Korman TP, Bowie JU2016 Dec 2228004831