Enzyme

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EC Tree
     4. Lyases
        4.1 Carbon-carbon lyases
            4.1.1 Carboxy-lyases
ID:4.1.1.25
Description:Tyrosine decarboxylase.
Alternative Name: L-tyrosine carboxy-lyase.
Prosite: PDOC00329;
PDB:
PDBScop
Cath: 3.40.640.10; 3.90.1150.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 4.1.1.25
BRENDA Enzyme Link: BRENDA 4.1.1.25
KEGG Enzyme Link: KEGG4.1.1.25
BioCyc Enzyme Link: BioCyc 4.1.1.25
ExPASy Enzyme Link: ExPASy4.1.1.25
EC2PDB Enzyme Link: EC2PDB 4.1.1.25
ExplorEnz Enzyme Link: ExplorEnz 4.1.1.25
PRIAM enzyme-specific profiles Link: PRIAM 4.1.1.25
IntEnz Enzyme Link: IntEnz 4.1.1.25
MEDLINE Enzyme Link: MEDLINE 4.1.1.25
MSA:

4.1.1.25;

Phylogenetic Tree:

4.1.1.25;

Uniprot:
M-CSA:
RHEA:14345 H(+) + L-tyrosine = CO2 + tyramine
RULE(radius=1) [*:1]=[C;H0;+0:2](-[OH;+0:3])-[CH;+0:4](-[*:5])-[*:6].[H+;H0:7]>>[*:5]-[CH2;+0:4]-[*:6].[*:1]=[C;H0;+0:2]=[O;H0;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The decarboxylation of L-phenylalanine by Streptococcus faecalis R.McGILVERY RW, COHEN PP1948 Jul18871240
Characterization of rice tryptophan decarboxylases and their direct involvement in serotonin biosynthesis in transgenic rice.Kang S, Kang K, Lee K, Back K2007 Dec17763868
Tyramine Functions independently of octopamine in the Caenorhabditis elegans nervous system.Alkema MJ, Hunter-Ensor M, Ringstad N, Horvitz HR2005 Apr 2115848803
Identification and characterization of a L-tyrosine decarboxylase in Methanocaldococcus jannaschii.Kezmarsky ND, Xu H, Graham DE, White RH2005 Mar 1115715981
The steady state kinetics of tyrosine decarboxylase from Streptococcus faecalis.Orlacchio A, Borri-Voltattorni C1979 Jan-Feb121930
Identification of the Enterococcus faecalis tyrosine decarboxylase operon involved in tyramine production.Connil N, Le Breton Y, Dousset X, Auffray Y, Rincé A, Prévost H2002 Jul12089039