ID: | 4.1.1.25 | ||
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Description: | Tyrosine decarboxylase. | ||
Alternative Name: |
L-tyrosine carboxy-lyase. | ||
Prosite: | PDOC00329; | ||
PDB: |
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Cath: | 3.40.640.10; 3.90.1150.10; |
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Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.UniProtKB Enzyme Link: | UniProtKB 4.1.1.25 |
BRENDA Enzyme Link: | BRENDA 4.1.1.25 |
KEGG Enzyme Link: | KEGG4.1.1.25 |
BioCyc Enzyme Link: | BioCyc 4.1.1.25 |
ExPASy Enzyme Link: | ExPASy4.1.1.25 |
EC2PDB Enzyme Link: | EC2PDB 4.1.1.25 |
ExplorEnz Enzyme Link: | ExplorEnz 4.1.1.25 |
PRIAM enzyme-specific profiles Link: | PRIAM 4.1.1.25 |
IntEnz Enzyme Link: | IntEnz 4.1.1.25 |
MEDLINE Enzyme Link: | MEDLINE 4.1.1.25 |
RHEA:14345 | H(+) + L-tyrosine = CO2 + tyramine |
RULE(radius=1) | [*:1]=[C;H0;+0:2](-[OH;+0:3])-[CH;+0:4](-[*:5])-[*:6].[H+;H0:7]>>[*:5]-[CH2;+0:4]-[*:6].[*:1]=[C;H0;+0:2]=[O;H0;+0:3] |
Reaction | ![]() |
Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
Title | Authors | Date | PubMed ID |
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The decarboxylation of L-phenylalanine by Streptococcus faecalis R. | McGILVERY RW, COHEN PP | 1948 Jul | 18871240 |
Characterization of rice tryptophan decarboxylases and their direct involvement in serotonin biosynthesis in transgenic rice. | Kang S, Kang K, Lee K, Back K | 2007 Dec | 17763868 |
Tyramine Functions independently of octopamine in the Caenorhabditis elegans nervous system. | Alkema MJ, Hunter-Ensor M, Ringstad N, Horvitz HR | 2005 Apr 21 | 15848803 |
Identification and characterization of a L-tyrosine decarboxylase in Methanocaldococcus jannaschii. | Kezmarsky ND, Xu H, Graham DE, White RH | 2005 Mar 11 | 15715981 |
The steady state kinetics of tyrosine decarboxylase from Streptococcus faecalis. | Orlacchio A, Borri-Voltattorni C | 1979 Jan-Feb | 121930 |
Identification of the Enterococcus faecalis tyrosine decarboxylase operon involved in tyramine production. | Connil N, Le Breton Y, Dousset X, Auffray Y, Rincé A, Prévost H | 2002 Jul | 12089039 |