| ID: | 4.1.1.25 | ||
|---|---|---|---|
| Description: | Tyrosine decarboxylase. | ||
| Alternative Name: |
L-tyrosine carboxy-lyase. | ||
| Prosite: | PDOC00329; | ||
| PDB: |
|
||
| Cath: | 3.40.640.10; 3.90.1150.10; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 4.1.1.25 |
| BRENDA Enzyme Link: | BRENDA 4.1.1.25 |
| KEGG Enzyme Link: | KEGG4.1.1.25 |
| BioCyc Enzyme Link: | BioCyc 4.1.1.25 |
| ExPASy Enzyme Link: | ExPASy4.1.1.25 |
| EC2PDB Enzyme Link: | EC2PDB 4.1.1.25 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.1.1.25 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.1.1.25 |
| IntEnz Enzyme Link: | IntEnz 4.1.1.25 |
| MEDLINE Enzyme Link: | MEDLINE 4.1.1.25 |
| RHEA:14345 | H(+) + L-tyrosine = CO2 + tyramine |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[OH;+0:3])-[CH;+0:4](-[*:5])-[*:6].[H+;H0:7]>>[*:5]-[CH2;+0:4]-[*:6].[*:1]=[C;H0;+0:2]=[O;H0;+0:3] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The decarboxylation of L-phenylalanine by Streptococcus faecalis R. | McGILVERY RW, COHEN PP | 1948 Jul | 18871240 |
| Characterization of rice tryptophan decarboxylases and their direct involvement in serotonin biosynthesis in transgenic rice. | Kang S, Kang K, Lee K, Back K | 2007 Dec | 17763868 |
| Tyramine Functions independently of octopamine in the Caenorhabditis elegans nervous system. | Alkema MJ, Hunter-Ensor M, Ringstad N, Horvitz HR | 2005 Apr 21 | 15848803 |
| Identification and characterization of a L-tyrosine decarboxylase in Methanocaldococcus jannaschii. | Kezmarsky ND, Xu H, Graham DE, White RH | 2005 Mar 11 | 15715981 |
| The steady state kinetics of tyrosine decarboxylase from Streptococcus faecalis. | Orlacchio A, Borri-Voltattorni C | 1979 Jan-Feb | 121930 |
| Identification of the Enterococcus faecalis tyrosine decarboxylase operon involved in tyramine production. | Connil N, Le Breton Y, Dousset X, Auffray Y, Rincé A, Prévost H | 2002 Jul | 12089039 |