Enzyme

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     4. Lyases
        4.1 Carbon-carbon lyases
            4.1.1 Carboxy-lyases
ID:4.1.1.37
Description:Uroporphyrinogen decarboxylase.
Alternative Name: Uroporphyrinogen-III carboxy-lyase.
Uroporphyrinogen III decarboxylase.
Prosite: PDOC00705;
PDB:
PDBScop
3GW3 8027956; 8040335;
3GW0 8027956; 8040335;
3GVV 8027956; 8040335;
3GVR 8027956; 8040335;
3GVQ 8027956; 8040335;
 » show all

Cath: 3.20.20.210;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 4.1.1.37
BRENDA Enzyme Link: BRENDA 4.1.1.37
KEGG Enzyme Link: KEGG4.1.1.37
BioCyc Enzyme Link: BioCyc 4.1.1.37
ExPASy Enzyme Link: ExPASy4.1.1.37
EC2PDB Enzyme Link: EC2PDB 4.1.1.37
ExplorEnz Enzyme Link: ExplorEnz 4.1.1.37
PRIAM enzyme-specific profiles Link: PRIAM 4.1.1.37
IntEnz Enzyme Link: IntEnz 4.1.1.37
MEDLINE Enzyme Link: MEDLINE 4.1.1.37
MSA:

4.1.1.37;

Phylogenetic Tree:

4.1.1.37;

Uniprot:
M-CSA:
RHEA:19865 4 H(+) + uroporphyrinogen III = 4 CO2 + coproporphyrinogen III
RULE(radius=1) [C:1][C:2](=[O:3])[OH:4]>>[C:1].[O:3]=[C:2]=[O:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Porphyrin biosynthesis. VII. Porphyrinogen carboxy-lyase from avian erythrocytes. Purification and properties.Tomio JM, García RC, San Martín de Viale LC, Grinstein M1970 Feb 114984554
Porphyrin biosynthesis in erythrocytes. III. Uroporphyrinogen and its decarboxylase.MAUZERALL D, GRANICK S1958 Jun13549492