EC number:4.1.1.6
| ID: | 4.1.1.6 |
|---|---|
| Description: | Cis-aconitate decarboxylase. |
| Alternative Name: |
Cis-aconitic decarboxylase. Cis-aconitate carboxy-lyase. CAD. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.1.1.6 |
| BRENDA Enzyme Link: | BRENDA 4.1.1.6 |
| KEGG Enzyme Link: | KEGG4.1.1.6 |
| BioCyc Enzyme Link: | BioCyc 4.1.1.6 |
| ExPASy Enzyme Link: | ExPASy4.1.1.6 |
| EC2PDB Enzyme Link: | EC2PDB 4.1.1.6 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.1.1.6 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.1.1.6 |
| IntEnz Enzyme Link: | IntEnz 4.1.1.6 |
| MEDLINE Enzyme Link: | MEDLINE 4.1.1.6 |
| RHEA:15253 | cis-aconitate + H(+) = CO2 + itaconate |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[OH;+0:3])-[CH;+0:4]=[*:5].[H+;H0:6]>>[*:1]=[C;H0;+0:2]=[O;H0;+0:3].[*:5]=[CH2;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production. | Michelucci A, Cordes T, Ghelfi J, Pailot A, Reiling N, Goldmann O, Binz T, Wegner A, Tallam A, Rausell A, Buttini M, Linster CL, Medina E, Balling R, Hiller K | 2013 May 7 | 23610393 |
| Cloning and functional characterization of the cis-aconitic acid decarboxylase (CAD) gene from Aspergillus terreus. | Kanamasa S, Dwiarti L, Okabe M, Park EY | 2008 Aug | 18584171 |
| Biosynthesis of itaconic acid in Aspergillus terreus. III. The properties and reaction mechanism of cis-aconitic acid decarboxylase. | BENTLEY R, THIESSEN CP | 1957 Jun | 13438855 |