EC number:4.1.1.85
| ID: | 4.1.1.85 |
|---|---|
| Description: | 3-dehydro-L-gulonate-6-phosphate decarboxylase. |
| Alternative Name: |
KGPDC. 3-keto-L-gulonate 6-phosphate decarboxylase. 3-dehydro-L-gulonate-6-phosphate carboxy-lyase. |
| Cath: | 3.20.20.150; 3.20.20.70; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 4.1.1.85 |
| BRENDA Enzyme Link: | BRENDA 4.1.1.85 |
| KEGG Enzyme Link: | KEGG4.1.1.85 |
| BioCyc Enzyme Link: | BioCyc 4.1.1.85 |
| ExPASy Enzyme Link: | ExPASy4.1.1.85 |
| EC2PDB Enzyme Link: | EC2PDB 4.1.1.85 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.1.1.85 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.1.1.85 |
| IntEnz Enzyme Link: | IntEnz 4.1.1.85 |
| MEDLINE Enzyme Link: | MEDLINE 4.1.1.85 |
| RHEA:14353 | 3-dehydro-L-gulonate 6-phosphate + H(+) = CO2 + L-xylulose 5-phosphate |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[OH;+0:3])-[CH;+0:4](-[*:5])-[*:6].[H+;H0:7]>>[*:5]-[CH2;+0:4]-[*:6].[*:1]=[C;H0;+0:2]=[O;H0;+0:3] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: crystallographic evidence for a proton relay system in the active site of 3-keto-L-gulonate 6-phosphate decarboxylase. | Wise EL, Yew WS, Gerlt JA, Rayment I | 2004 Jun 1 | 15157078 |
| Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: mechanistic evidence for a proton relay system in the active site of 3-keto-L-gulonate 6-phosphate decarboxylase. | Yew WS, Wise EL, Rayment I, Gerlt JA | 2004 Jun 1 | 15157077 |
| Structural evidence for a 1,2-enediolate intermediate in the reaction catalyzed by 3-keto-L-gulonate 6-phosphate decarboxylase, a member of the orotidine 5'-monophosphate decarboxylase suprafamily. | Wise EL, Yew WS, Gerlt JA, Rayment I | 2003 Oct 28 | 14567674 |
| Homologous (beta/alpha)8-barrel enzymes that catalyze unrelated reactions: orotidine 5'-monophosphate decarboxylase and 3-keto-L-gulonate 6-phosphate decarboxylase. | Wise E, Yew WS, Babbitt PC, Gerlt JA, Rayment I | 2002 Mar 26 | 11900527 |