EC number:4.1.1.88
| ID: | 4.1.1.88 | ||
|---|---|---|---|
| Description: | Biotin-independent malonate decarboxylase. | ||
| Alternative Name: |
MDC. Malonate decarboxylase. Malonate carboxy-lyase (biotin-independent). | ||
| Prosite: | PDOC50980; | ||
| PDB: |
|
||
| Cath: | 1.10.110.40; 1.10.1200.10; 1.10.1470.20; 1.10.287.1960; 1.10.287.3140; 1.20.1050.120; 1.20.5.3540; 3.20.20.70; 3.30.1120.10; 3.30.1120.100; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 4.1.1.88 |
| BRENDA Enzyme Link: | BRENDA 4.1.1.88 |
| KEGG Enzyme Link: | KEGG4.1.1.88 |
| BioCyc Enzyme Link: | BioCyc 4.1.1.88 |
| ExPASy Enzyme Link: | ExPASy4.1.1.88 |
| EC2PDB Enzyme Link: | EC2PDB 4.1.1.88 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.1.1.88 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.1.1.88 |
| IntEnz Enzyme Link: | IntEnz 4.1.1.88 |
| MEDLINE Enzyme Link: | MEDLINE 4.1.1.88 |
| RHEA:25896 | H(+) + malonate = acetate + CO2 |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[OH;+0:3])-[CH2;+0:4]-[*:5].[H+;H0:6]>>[*:5]-[CH3;+0:4].[*:1]=[C;H0;+0:2]=[O;H0;+0:3] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Malonate decarboxylase of Pseudomonas putida is composed of five subunits. | Chohnan S, Fujio T, Takaki T, Yonekura M, Nishihara H, Takamura Y | 1998 Dec 1 | 9851033 |
| Malonate metabolism: biochemistry, molecular biology, physiology, and industrial application. | Kim YS | 2002 Sep 30 | 12359084 |
| Sequence of a gene cluster from Klebsiella pneumoniae encoding malonate decarboxylase and expression of the enzyme in Escherichia coli. | Hoenke S, Schmid M, Dimroth P | 1997 Jun 1 | 9208947 |
| Enzymic and genetic basis for bacterial growth on malonate. | Dimroth P, Hilbi H | 1997 Jul | 11902724 |
| Functional evaluation of the genes involved in malonate decarboxylation by Acinetobacter calcoaceticus. | Koo JH, Kim YS | 1999 Dec | 10561613 |
| Identification of the active site of phosphoribosyl-dephospho-coenzyme A transferase and relationship of the enzyme to an ancient class of nucleotidyltransferases. | Hoenke S, Schmid M, Dimroth P | 2000 Oct 31 | 11052676 |
| Malonate decarboxylase of Klebsiella pneumoniae catalyses the turnover of acetyl and malonyl thioester residues on a coenzyme-A-like prosthetic group. | Schmid M, Berg M, Hilbi H, Dimroth P | 1996 Apr 1 | 8620876 |
| Stereochemical course of biotin-independent malonate decarboxylase catalysis. | Handa S, Koo JH, Kim YS, Floss HG | 1999 Oct 1 | 10496981 |