| ID: | 4.1.1.94 |
|---|---|
| Description: | Ethylmalonyl-CoA decarboxylase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 4.1.1.94 |
| BRENDA Enzyme Link: | BRENDA 4.1.1.94 |
| KEGG Enzyme Link: | KEGG4.1.1.94 |
| BioCyc Enzyme Link: | BioCyc 4.1.1.94 |
| ExPASy Enzyme Link: | ExPASy4.1.1.94 |
| EC2PDB Enzyme Link: | EC2PDB 4.1.1.94 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.1.1.94 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.1.1.94 |
| IntEnz Enzyme Link: | IntEnz 4.1.1.94 |
| MEDLINE Enzyme Link: | MEDLINE 4.1.1.94 |
| RHEA:32131 | (2S)-ethylmalonyl-CoA + H(+) = butanoyl-CoA + CO2 |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[OH;+0:3])-[CH;+0:4](-[*:5])-[*:6].[H+;H0:7]>>[*:5]-[CH2;+0:4]-[*:6].[*:1]=[C;H0;+0:2]=[O;H0;+0:3] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Ethylmalonyl-CoA decarboxylase, a new enzyme involved in metabolite proofreading. | Linster CL, Noël G, Stroobant V, Vertommen D, Vincent MF, Bommer GT, Veiga-da-Cunha M, Van Schaftingen E | 2011 Dec 16 | 22016388 |
| Metabolite damage and its repair or pre-emption. | Linster CL, Van Schaftingen E, Hanson AD | 2013 Feb | 23334546 |