EC number:4.1.2.10
| ID: | 4.1.2.10 |
|---|---|
| Description: | (R)-mandelonitrile lyase. |
| Alternative Name: |
Mandelonitrile benzaldehyde-lyase. Hydroxynitrile lyase. D-oxynitrilase. (R)-oxynitrilase. |
| Cath: | 1.20.5.2390; 3.30.410.40; 3.50.50.60; 3.40.50.11320; 3.40.50.1820; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 4.1.2.10 |
| BRENDA Enzyme Link: | BRENDA 4.1.2.10 |
| KEGG Enzyme Link: | KEGG4.1.2.10 |
| BioCyc Enzyme Link: | BioCyc 4.1.2.10 |
| ExPASy Enzyme Link: | ExPASy4.1.2.10 |
| EC2PDB Enzyme Link: | EC2PDB 4.1.2.10 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.1.2.10 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.1.2.10 |
| IntEnz Enzyme Link: | IntEnz 4.1.2.10 |
| MEDLINE Enzyme Link: | MEDLINE 4.1.2.10 |
| RHEA:18313 | (R)-mandelonitrile = benzaldehyde + hydrogen cyanide |
| RULE(radius=1) | [*:1]#[C;H0;+0:2]-[CH;+0:3](-[*:4])-[OH;+0:5]>>[*:1]#[CH;+0:2].[*:4]-[CH;+0:3]=[O;H0;+0:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A rapid and sensitive spectrophotometric assay for prunasin hydrolase activity employing purified mandelonitrile lyase. | Gross M, Jacobs GH, Poulton JE | 1982 Jan 1 | 6803611 |
| Studies on the kinetics of cyanohydrin synthesis and cleavage by the the flavoenzyme oxynitrilase. | Jorns MS | 1980 | 6246955 |
| Uneven twins: comparison of two enantiocomplementary hydroxynitrile lyases with alpha/beta-hydrolase fold. | Guterl JK, Andexer JN, Sehl T, von Langermann J, Frindi-Wosch I, Rosenkranz T, Fitter J, Gruber K, Kragl U, Eggert T, Pohl M | 2009 May 20 | 19433222 |
| Substrate binding in the FAD-dependent hydroxynitrile lyase from almond provides insight into the mechanism of cyanohydrin formation and explains the absence of dehydrogenation activity. | Dreveny I, Andryushkova AS, Glieder A, Gruber K, Kratky C | 2009 Apr 21 | 19256550 |
| Purification and characterization of a novel (R)-hydroxynitrile lyase from Eriobotrya japonica (Loquat). | Ueatrongchit T, Kayo A, Komeda H, Asano Y, H-Kittikun A | 2008 Jun | 18540101 |
| An R-selective hydroxynitrile lyase from Arabidopsis thaliana with an alpha/beta-hydrolase fold. | Andexer J, von Langermann J, Mell A, Bocola M, Kragl U, Eggert T, Pohl M | 2007 | 17907254 |