EC number:4.1.2.14
| ID: | 4.1.2.14 |
|---|---|
| Description: | 2-dehydro-3-deoxy-phosphogluconate aldolase. |
| Alternative Name: |
Phospho-2-keto-3-deoxygluconate aldolase. Phospho-2-dehydro-3-deoxygluconate aldolase. KDPG-aldolase. 2-keto-3-deoxy-6-phosphogluconate aldolase. lyase. 2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate- |
| Prosite: | PDOC00144; |
| PDB: |
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| Cath: | 3.20.20.70; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.1.2.14 |
| BRENDA Enzyme Link: | BRENDA 4.1.2.14 |
| KEGG Enzyme Link: | KEGG4.1.2.14 |
| BioCyc Enzyme Link: | BioCyc 4.1.2.14 |
| ExPASy Enzyme Link: | ExPASy4.1.2.14 |
| EC2PDB Enzyme Link: | EC2PDB 4.1.2.14 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.1.2.14 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.1.2.14 |
| IntEnz Enzyme Link: | IntEnz 4.1.2.14 |
| MEDLINE Enzyme Link: | MEDLINE 4.1.2.14 |
| RHEA:17089 | 2-dehydro-3-deoxy-6-phospho-D-gluconate = D-glyceraldehyde 3-phosphate + pyruvate |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[CH;+0:3](-[*:4])-[OH;+0:5]>>[*:1]-[CH3;+0:2].[*:4]-[CH;+0:3]=[O;H0;+0:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The mechanism of 2-keto-3-deoxy-6-phosphogluconate aldolase. 3. Nature of the inactivation by fluorodinitrobenzene. | Barran LR, Wood WA | 1971 Jun 25 | 5561473 |
| CRYSTALLIZATION AND CHARACTERISTICS OF 2-KETO-3-DEOXY-6-PHOSPHOGLUCONIC ALDOLASE. | MELOCHE HP, WOOD WA | 1964 Oct | 14245411 |
| An extremely thermostable aldolase from Sulfolobus solfataricus with specificity for non-phosphorylated substrates. | Buchanan CL, Connaris H, Danson MJ, Reeve CD, Hough DW | 1999 Nov 1 | 10527934 |
| Promiscuity in the part-phosphorylative Entner-Doudoroff pathway of the archaeon Sulfolobus solfataricus. | Lamble HJ, Theodossis A, Milburn CC, Taylor GL, Bull SD, Hough DW, Danson MJ | 2005 Dec 19 | 16330030 |
| Prediction of enzymatic pathways by integrative pathway mapping. | Calhoun S, Korczynska M, Wichelecki DJ, San Francisco B, Zhao S, Rodionov DA, Vetting MW, Al-Obaidi NF, Lin H, O'Meara MJ, Scott DA, Morris JH, Russel D, Almo SC, Osterman AL, Gerlt JA, Jacobson MP, Shoichet BK, Sali A | 2018 Jan 29 | 29377793 |