Enzyme

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EC Tree
     4. Lyases
        4.1 Carbon-carbon lyases
            4.1.2 Aldehyde-lyases
ID:4.1.2.34
Description:4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase.
Alternative Name: 2'-carboxybenzalpyruvate aldolase.
(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-formylbenzoate-lyase.
(3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 4.1.2.34
BRENDA Enzyme Link: BRENDA 4.1.2.34
KEGG Enzyme Link: KEGG4.1.2.34
BioCyc Enzyme Link: BioCyc 4.1.2.34
ExPASy Enzyme Link: ExPASy4.1.2.34
EC2PDB Enzyme Link: EC2PDB 4.1.2.34
ExplorEnz Enzyme Link: ExplorEnz 4.1.2.34
PRIAM enzyme-specific profiles Link: PRIAM 4.1.2.34
IntEnz Enzyme Link: IntEnz 4.1.2.34
MEDLINE Enzyme Link: MEDLINE 4.1.2.34
MSA:

4.1.2.34;

Phylogenetic Tree:

4.1.2.34;

Uniprot:
M-CSA:
RHEA:16453 (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate + H2O = 2-formylbenzoate + pyruvate
RULE(radius=1) [*:1]-[CH;+0:2]=[CH;+0:3]-[*:4].[OH2;+0:5]>>[*:1]-[CH3;+0:2].[*:4]-[CH;+0:3]=[O;H0;+0:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Biochemical and genetic characterization of trans-2'-carboxybenzalpyruvate hydratase-aldolase from a phenanthrene-degrading Nocardioides strain.Iwabuchi T, Harayama S1998 Feb9473051
Phthalate pathway of phenanthrene metabolism: formation of 2'-carboxybenzalpyruvate.Barnsley EA1983 Apr6833175