EC number:4.1.2.59

Enzyme

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EC Tree
     4. Lyases
        4.1 Carbon-carbon lyases
            4.1.2 Aldehyde-lyases
ID:4.1.2.59
Description:Dihydroneopterin phosphate aldolase.
Alternative Name: H(2)NMP aldolase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.1.2.59
BRENDA Enzyme Link: BRENDA 4.1.2.59
KEGG Enzyme Link: KEGG4.1.2.59
BioCyc Enzyme Link: BioCyc 4.1.2.59
ExPASy Enzyme Link: ExPASy4.1.2.59
EC2PDB Enzyme Link: EC2PDB 4.1.2.59
ExplorEnz Enzyme Link: ExplorEnz 4.1.2.59
PRIAM enzyme-specific profiles Link: PRIAM 4.1.2.59
IntEnz Enzyme Link: IntEnz 4.1.2.59
MEDLINE Enzyme Link: MEDLINE 4.1.2.59

EC number:4.1.2.59

MSA:

4.1.2.59;
Phylogenetic Tree:

4.1.2.59;
Uniprot:
M-CSA:
RHEA:51016 7,8-dihydroneopterin 3'-phosphate = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde phosphate
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[CH;+0:4](-[*:5])-[OH;+0:6]>>[*:1]-[CH2;+0:2]-[*:3].[*:5]-[CH;+0:4]=[O;H0;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Comparative genomics guided discovery of two missing archaeal enzyme families involved in the biosynthesis of the pterin moiety of tetrahydromethanopterin and tetrahydrofolate.de Crécy-Lagard V, Phillips G, Grochowski LL, El Yacoubi B, Jenney F, Adams MW, Murzin AG, White RH2012 Nov 1622931285