Enzyme

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     4. Lyases
        4.1 Carbon-carbon lyases
            4.1.3 Oxo-acid-lyases
ID:4.1.3.3
Description:N-acetylneuraminate lyase.
Alternative Name: N-acetylneuraminic acid aldolase.
N-acetylneuraminate pyruvate-lyase.
Prosite: PDOC00569;
PDB:
PDBScop
4UUI 8032147; 8044525; 8032147; 8044525; 8032147; 8044525; 8032147; 8044525;
4BWL 8032147; 8044525; 8032147; 8044525; 8032147; 8044525; 8032147; 8044525;
3LCX 8032147; 8044525; 8032147; 8044525; 8032147; 8044525; 8032147; 8044525;
3LCW 8032147; 8044525; 8032147; 8044525; 8032147; 8044525; 8032147; 8044525;
3LCL 8032147; 8044525; 8032147; 8044525; 8032147; 8044525; 8032147; 8044525;
 » show all

Cath: 3.20.20.70;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 4.1.3.3
BRENDA Enzyme Link: BRENDA 4.1.3.3
KEGG Enzyme Link: KEGG4.1.3.3
BioCyc Enzyme Link: BioCyc 4.1.3.3
ExPASy Enzyme Link: ExPASy4.1.3.3
EC2PDB Enzyme Link: EC2PDB 4.1.3.3
ExplorEnz Enzyme Link: ExplorEnz 4.1.3.3
PRIAM enzyme-specific profiles Link: PRIAM 4.1.3.3
IntEnz Enzyme Link: IntEnz 4.1.3.3
MEDLINE Enzyme Link: MEDLINE 4.1.3.3
MSA:

4.1.3.3;

Phylogenetic Tree:

4.1.3.3;

Uniprot:
M-CSA:
RHEA:23296 N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate
RULE(radius=1) [*:1]-[C;H0;+0:2]1(-[OH;+0:3])-[CH2;+0:4]-[CH;+0:5](-[OH;+0:6])-[*:7]-[*:8]-[O;H0;+0:9]-1>>[*:1]-[C;H0;+0:2](-[CH3;+0:4])=[O;H0;+0:3].[O;H0;+0:6]=[CH;+0:5]-[*:7]-[*:8]-[OH;+0:9]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction