EC number:4.1.3.36

Enzyme

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     4. Lyases
        4.1 Carbon-carbon lyases
            4.1.3 Oxo-acid-lyases
ID:4.1.3.36
Description:1,4-dihydroxy-2-naphthoyl-CoA synthase.
Alternative Name: o-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing).
Naphthoate synthase.
Dihydroxynaphthoic acid synthetase.
DHNA synthetase.
Prosite: PDOC00150;
PDB:
PDBScop
Cath: 1.10.12.10; 1.10.12.100; 3.90.226.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.1.3.36
BRENDA Enzyme Link: BRENDA 4.1.3.36
KEGG Enzyme Link: KEGG4.1.3.36
BioCyc Enzyme Link: BioCyc 4.1.3.36
ExPASy Enzyme Link: ExPASy4.1.3.36
EC2PDB Enzyme Link: EC2PDB 4.1.3.36
ExplorEnz Enzyme Link: ExplorEnz 4.1.3.36
PRIAM enzyme-specific profiles Link: PRIAM 4.1.3.36
IntEnz Enzyme Link: IntEnz 4.1.3.36
MEDLINE Enzyme Link: MEDLINE 4.1.3.36

EC number:4.1.3.36

MSA:

4.1.3.36;
Phylogenetic Tree:

4.1.3.36;
Uniprot:
M-CSA:
RHEA:26562 2-succinylbenzoyl-CoA + H(+) = 1,4-dihydroxy-2-naphthoyl-CoA + H2O
RULE(radius=1) ([*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[OH;+0:5].[*:6]-[c;H0;+0:7]1:[*:8]:[cH;+0:9]:[cH;+0:10]:[*:11]:[c;H0;+0:12]:1-[C;H0;+0:13](=[O;H0;+0:14])-[CH2;+0:15]-[CH2;+0:16]-[C;H0;+0:17](-[*:18])=[O;H0;+0:19]).[H+;H0:20]>>([*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[OH;+0:19].[*:6]-[c;H0;+0:7]1:[*:8]:[c;H0;+0:9](-[OH;+0:14]):[c;H0;+0:10]2:[*:11]:[cH;+0:12]:[cH;+0:13]:[cH;+0:15]:[c;H0;+0:16]:2:[c;H0;+0:17]:1-[*:18]).[OH2;+0:5]
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References

TitleAuthorsDatePubMed ID
Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis.Truglio JJ, Theis K, Feng Y, Gajda R, Machutta C, Tonge PJ, Kisker C2003 Oct 2412909628