EC number:4.1.3.42
| ID: | 4.1.3.42 |
|---|---|
| Description: | (4S)-4-hydroxy-2-oxoglutarate aldolase. |
| Alternative Name: |
Hydroxyketoglutaric aldolase. 4-hydroxy-2-ketoglutaric aldolase. 2-keto-4-hydroxyglutaric aldolase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.1.3.42 |
| BRENDA Enzyme Link: | BRENDA 4.1.3.42 |
| KEGG Enzyme Link: | KEGG4.1.3.42 |
| BioCyc Enzyme Link: | BioCyc 4.1.3.42 |
| ExPASy Enzyme Link: | ExPASy4.1.3.42 |
| EC2PDB Enzyme Link: | EC2PDB 4.1.3.42 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.1.3.42 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.1.3.42 |
| IntEnz Enzyme Link: | IntEnz 4.1.3.42 |
| MEDLINE Enzyme Link: | MEDLINE 4.1.3.42 |
| RHEA:35639 | L-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[*:3])-[CH2;+0:4]-[CH;+0:5](-[*:6])-[OH;+0:7]>>[*:6]-[C;H0;+0:5](-[CH3;+0:4])=[O;H0;+0:7].[*:1]-[CH;+0:2]=[*:3] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification, substrate specificity and binding, -decarboxylase activity, and other properties of Escherichia coli 2-keto-4-hydroxyglutarate aldolase. | Nishihara H, Dekker EE | 1972 Aug 25 | 4560498 |
| Cloning, nucleotide sequence, overexpression, and inactivation of the Escherichia coli 2-keto-4-hydroxyglutarate aldolase gene. | Patil RV, Dekker EE | 1992 Jan | 1339418 |