EC number:4.1.99.3

Enzyme

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     4. Lyases
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ID:4.1.99.3
Description:Deoxyribodipyrimidine photo-lyase.
Alternative Name: Photoreactivating enzyme.
DNA photolyase.
Prosite: PDOC00832; PDOC00331;
PDB:
PDBScop
1NP7 8031526; 8031527; 8043904; 8043905; 8031526; 8043904; 8031527; 8043905;
2J09 8030562; 8030564; 8042941; 8042943;
2J08 8030562; 8030564; 8042941; 8042943;
2J07 8030562; 8030564; 8042941; 8042943;
1IQU 8030562; 8030564; 8042941; 8042943;
 » show all
Cath: 1.10.579.10; 3.40.50.620; 1.25.40.80;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.1.99.3
BRENDA Enzyme Link: BRENDA 4.1.99.3
KEGG Enzyme Link: KEGG4.1.99.3
BioCyc Enzyme Link: BioCyc 4.1.99.3
ExPASy Enzyme Link: ExPASy4.1.99.3
EC2PDB Enzyme Link: EC2PDB 4.1.99.3
ExplorEnz Enzyme Link: ExplorEnz 4.1.99.3
PRIAM enzyme-specific profiles Link: PRIAM 4.1.99.3
IntEnz Enzyme Link: IntEnz 4.1.99.3
MEDLINE Enzyme Link: MEDLINE 4.1.99.3

EC number:4.1.99.3

MSA:

4.1.99.3;
Phylogenetic Tree:

4.1.99.3;
Uniprot:
M-CSA:
RHEA:10672 cyclobutadithymidine in DNA = thymidine dimer in DNA
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[C;H0;+0:3](=[*:4])-[NH;+0:5]-[C;H0;+0:6](=[*:7])-[C;H0;+0:8]2(-[*:9])-[CH;+0:10]-1-[CH;+0:11]1-[N;H0;+0:12](-[*:13])-[C;H0;+0:14](=[*:15])-[NH;+0:16]-[C;H0;+0:17](=[*:18])-[C;H0;+0:19]-1-2-[*:20]>>([*:1]-[n;H0;+0:2]1:[cH;+0:10]:[c;H0;+0:8](-[*:9]):[c;H0;+0:6](=[*:7]):[nH;+0:5]:[c;H0;+0:3]:1=[*:4].[*:15]=[c;H0;+0:14]1:[nH;+0:16]:[c;H0;+0:17](=[*:18]):[c;H0;+0:19](-[*:20]):[cH;+0:11]:[n;H0;+0:12]:1-[*:13])
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References

TitleAuthorsDatePubMed ID
Studies on a DNA photoreactivating enzyme from Streptomyces griseus. II. Purification of the enzyme.Eker AP, Fichtinger-Schepman AM1975 Jan 6804322
Action mechanism of Escherichia coli DNA photolyase. I. Formation of the enzyme-substrate complex.Sancar GB, Smith FW, Reid R, Payne G, Levy M, Sancar A1987 Jan 53539939
Direct observation of thymine dimer repair in DNA by photolyase.Kao YT, Saxena C, Wang L, Sancar A, Zhong D2005 Nov 816169906