EC number:4.2.1.103

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.103
Description:Cyclohexyl-isocyanide hydratase.
Alternative Name: Isonitrile hydratase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.103
BRENDA Enzyme Link: BRENDA 4.2.1.103
KEGG Enzyme Link: KEGG4.2.1.103
BioCyc Enzyme Link: BioCyc 4.2.1.103
ExPASy Enzyme Link: ExPASy4.2.1.103
EC2PDB Enzyme Link: EC2PDB 4.2.1.103
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.103
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.103
IntEnz Enzyme Link: IntEnz 4.2.1.103
MEDLINE Enzyme Link: MEDLINE 4.2.1.103

EC number:4.2.1.103

MSA:

4.2.1.103;
Phylogenetic Tree:

4.2.1.103;
Uniprot:
M-CSA:
RHEA:18197 H(+) + N-cyclohexylformamide = cyclohexyl isocyanide + H2O
RULE(radius=1) [*:1]-[NH;+0:2]-[CH;+0:3]=[O;H0;+0:4].[H+;H0:5]>>[*:1]-[N+;H0:2]#[CH;+0:3].[OH2;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Isonitrile hydratase from Pseudomonas putida N19-2. Cloning, sequencing, gene expression, and identification of its active acid residue.Goda M, Hashimoto Y, Takase M, Herai S, Iwahara Y, Higashibata H, Kobayashi M2002 Nov 2912244065
Discovery of a novel enzyme, isonitrile hydratase, involved in nitrogen-carbon triple bond cleavage.Goda M, Hashimoto Y, Shimizu S, Kobayashi M2001 Jun 2911306561