EC number:4.2.1.108

Enzyme

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     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.108
Description:Ectoine synthase.
Alternative Name: N-acetyldiaminobutyrate dehydratase.
N-acetyldiaminobutanoate dehydratase.
L-ectoine synthase.
Cath: 3.40.630.30; 2.60.120.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.108
BRENDA Enzyme Link: BRENDA 4.2.1.108
KEGG Enzyme Link: KEGG4.2.1.108
BioCyc Enzyme Link: BioCyc 4.2.1.108
ExPASy Enzyme Link: ExPASy4.2.1.108
EC2PDB Enzyme Link: EC2PDB 4.2.1.108
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.108
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.108
IntEnz Enzyme Link: IntEnz 4.2.1.108
MEDLINE Enzyme Link: MEDLINE 4.2.1.108

EC number:4.2.1.108

MSA:

4.2.1.108;
Phylogenetic Tree:

4.2.1.108;
Uniprot:
M-CSA:
RHEA:17281 (2S)-4-acetamido-2-aminobutanoate = H2O + L-ectoine
RULE(radius=1) ([*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[NH2;+0:6])>>[*:1]-[C;H0;+0:2](-[*:3])=[N;H0;+0:6]-[*:5].[OH2;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Characterization of genes for the biosynthesis of the compatible solute ectoine from Marinococcus halophilus and osmoregulated expression in Escherichia coli.Louis P, Galinski EA1997 Apr9141677
Osmotically regulated synthesis of the compatible solute ectoine in Bacillus pasteurii and related Bacillus spp.Kuhlmann AU, Bremer E2002 Feb11823218
Characterization of biosynthetic enzymes for ectoine as a compatible solute in a moderately halophilic eubacterium, Halomonas elongata.Ono H, Sawada K, Khunajakr N, Tao T, Yamamoto M, Hiramoto M, Shinmyo A, Takano M, Murooka Y1999 Jan9864317