Enzyme

Download
EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.110
Description:Aldos-2-ulose dehydratase.
Alternative Name: Pyranosone dehydratase.
AUDH.
1,5-anhydro-D-fructose dehydratase (microthecin-forming).
Cath: 2.60.120.990; 2.60.40.1180; 2.60.40.1760; 2.80.10.50;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.110
BRENDA Enzyme Link: BRENDA 4.2.1.110
KEGG Enzyme Link: KEGG4.2.1.110
BioCyc Enzyme Link: BioCyc 4.2.1.110
ExPASy Enzyme Link: ExPASy4.2.1.110
EC2PDB Enzyme Link: EC2PDB 4.2.1.110
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.110
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.110
IntEnz Enzyme Link: IntEnz 4.2.1.110
MEDLINE Enzyme Link: MEDLINE 4.2.1.110
MSA:

4.2.1.110;

Phylogenetic Tree:

4.2.1.110;

Uniprot:
M-CSA:
RHEA:12100 1,5-anhydro-D-fructose = H2O + microthecin
RULE(radius=1) [*:1]-[CH;+0:2]1-[*:3]-[*:4]-[C;H0;+0:5](=[O;H0;+0:6])-[CH;+0:7](-[OH;+0:8])-[CH;+0:9]-1-[OH;+0:10]>>[*:1]-[C;H0;+0:2]1(-[OH;+0:8])-[*:3]-[*:4]-[CH;+0:5]=[CH;+0:7]-[C;H0;+0:9]-1=[O;H0;+0:10].[OH2;+0:6]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Pyranosone dehydratase from the basidiomycete Phanerochaete chrysosporium: improved purification, and identification of 6-deoxy-D-glucosone and D-xylosone reaction products.Gabriel J, Volc J, Sedmera P, Daniel G, Kubátová E19938352649
The anhydrofructose pathway and its possible role in stress response and signaling.Yu S, Fiskesund R2006 Sep16822618
Enzymatic description of the anhydrofructose pathway of glycogen degradation II. Gene identification and characterization of the reactions catalyzed by aldos-2-ulose dehydratase that converts 1,5-anhydro-D-fructose to microthecin with ascopyrone M as the intermediate.Yu S2005 May 2515716041
Enzymatic description of the anhydrofructose pathway of glycogen degradation; I. Identification and purification of anhydrofructose dehydratase, ascopyrone tautomerase and alpha-1,4-glucan lyase in the fungus Anthracobia melaloma.Yu S, Refdahl C, Lundt I2004 May 315110094