EC number:4.2.1.122
| ID: | 4.2.1.122 |
|---|---|
| Description: | Tryptophan synthase (indole-salvaging). |
| Alternative Name: |
Tryptophan synthase beta-2. |
| Cath: | 3.20.20.70; 3.40.50.1100; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.2.1.122 |
| BRENDA Enzyme Link: | BRENDA 4.2.1.122 |
| KEGG Enzyme Link: | KEGG4.2.1.122 |
| BioCyc Enzyme Link: | BioCyc 4.2.1.122 |
| ExPASy Enzyme Link: | ExPASy4.2.1.122 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.1.122 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.1.122 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.1.122 |
| IntEnz Enzyme Link: | IntEnz 4.2.1.122 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.1.122 |
EC number:4.2.1.122
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:26434 | indole + L-serine = H2O + L-tryptophan |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[OH;+0:3].[*:4]:[cH;+0:5]:[*:6]>>[*:1]-[CH2;+0:2]-[c;H0;+0:5](:[*:4]):[*:6].[OH2;+0:3] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Three-dimensional structure of the tryptophan synthase alpha 2 beta 2 multienzyme complex from Salmonella typhimurium. | Hyde CC, Ahmed SA, Padlan EA, Miles EW, Davies DR | 1988 Nov 25 | 3053720 |
| ON THE SEPARATION OF THE TRYPTOPHAN SYNTHETASE OF ESCHERICHIA COLI INTO TWO PROTEIN COMPONENTS. | Crawford IP, Yanofsky C | 1958 Dec 15 | 16590328 |
| Proteomic survey of copper-binding proteins in Arabidopsis roots by immobilized metal affinity chromatography and mass spectrometry. | Kung CC, Huang WN, Huang YC, Yeh KC | 2006 May | 16526091 |
| Mechanisms of monovalent cation action in enzyme catalysis: the tryptophan synthase alpha-, beta-, and alpha beta-reactions. | Woehl E, Dunn MF | 1999 Jun 1 | 10353823 |
| A novel tryptophan synthase beta-subunit from the hyperthermophile Thermotoga maritima. Quaternary structure, steady-state kinetics, and putative physiological role. | Hettwer S, Sterner R | 2002 Mar 8 | 11756459 |