EC number:4.2.1.130

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.130
Description:D-lactate dehydratase.
Alternative Name: Glyoxylase III.
Cath: 3.40.50.880;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.130
BRENDA Enzyme Link: BRENDA 4.2.1.130
KEGG Enzyme Link: KEGG4.2.1.130
BioCyc Enzyme Link: BioCyc 4.2.1.130
ExPASy Enzyme Link: ExPASy4.2.1.130
EC2PDB Enzyme Link: EC2PDB 4.2.1.130
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.130
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.130
IntEnz Enzyme Link: IntEnz 4.2.1.130
MEDLINE Enzyme Link: MEDLINE 4.2.1.130

EC number:4.2.1.130

MSA:

4.2.1.130;
Phylogenetic Tree:

4.2.1.130;
Uniprot:
M-CSA:
RHEA:27754 H2O + methylglyoxal = (R)-lactate + H(+)
RULE(radius=1) [*:1]=[CH;+0:2]-[C;H0;+0:3](-[*:4])=[O;H0;+0:5].[OH2;+0:6]>>[*:1]=[C;H0;+0:2](-[OH;+0:6])-[CH;+0:3](-[*:4])-[OH;+0:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Identification of glutathione (GSH)-independent glyoxalase III from Schizosaccharomyces pombe.Zhao Q, Su Y, Wang Z, Chen C, Wu T, Huang Y2014 Apr 2324758716
A glutathione-independent glyoxalase of the DJ-1 superfamily plays an important role in managing metabolically generated methylglyoxal in Candida albicans.Hasim S, Hussin NA, Alomar F, Bidasee KR, Nickerson KW, Wilson MA2014 Jan 1724302734