EnzyMine

Download

EC Tree

4. Lyases

4.2 Carbon-oxygen lyases

4.2.1 Hydro-lyases

ID:	4.2.1.139
Description:	Pterocarpan synthase.
Alternative Name:	Medicarpin synthase. Medicarpan synthase. 7,2'-dihydroxy-4'-methoxyisoflavanol dehydratase. 2'-hydroxyisoflavanol 4,2'-dehydratase. 2',7-dihydroxy-4'-methoxyisoflavanol dehydratase.
Cath:	3.40.50.720;

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

PDB	Click once to unfold,double click to fold.

UniProtKB Enzyme Link:	UniProtKB 4.2.1.139
BRENDA Enzyme Link:	BRENDA 4.2.1.139
KEGG Enzyme Link:	KEGG4.2.1.139
BioCyc Enzyme Link:	BioCyc 4.2.1.139
ExPASy Enzyme Link:	ExPASy4.2.1.139
EC2PDB Enzyme Link:	EC2PDB 4.2.1.139
ExplorEnz Enzyme Link:	ExplorEnz 4.2.1.139
PRIAM enzyme-specific profiles Link:	PRIAM 4.2.1.139
IntEnz Enzyme Link:	IntEnz 4.2.1.139
MEDLINE Enzyme Link:	MEDLINE 4.2.1.139

RHEA:35811	4'-methoxyisoflavan-2',4,7-triol = (-)-medicarpin + H2O
RULE(radius=1)	([:1]-[CH;+0:2](-[:3])-[OH;+0:4].[:5]-[OH;+0:6])>>[:5]-[O;H0;+0:6]-[CH;+0:2](-[:1])-[:3].[OH2;+0:4]
Reaction
Core-to-Core	More

Title	Authors	Date	PubMed ID
The Missing Link in Leguminous Pterocarpan Biosynthesis is a Dirigent Domain-Containing Protein with Isoflavanol Dehydratase Activity.	Uchida K, Akashi T, Aoki T	2017 Feb 1	28394400
Conversion of vestitone to medicarpin in alfalfa (Medicago sativa L.) is catalyzed by two independent enzymes. Identification, purification, and characterization of vestitone reductase and 7,2'-dihydroxy-4'-methoxyisoflavanol dehydratase.	Guo L, Dixon RA, Paiva NL	1994 Sep 2	8071365
The 'pterocarpan synthase' of alfalfa: association and co-induction of vestitone reductase and 7,2'-dihydroxy-4'-methoxy-isoflavanol (DMI) dehydratase, the two final enzymes in medicarpin biosynthesis.	Guo L, Dixon RA, Paiva NL	1994 Dec 19	7805842