EC number:4.2.1.142

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.142
Description:5'-oxoaverantin cyclase.
Alternative Name: OAVN cyclase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.142
BRENDA Enzyme Link: BRENDA 4.2.1.142
KEGG Enzyme Link: KEGG4.2.1.142
BioCyc Enzyme Link: BioCyc 4.2.1.142
ExPASy Enzyme Link: ExPASy4.2.1.142
EC2PDB Enzyme Link: EC2PDB 4.2.1.142
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.142
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.142
IntEnz Enzyme Link: IntEnz 4.2.1.142
MEDLINE Enzyme Link: MEDLINE 4.2.1.142

EC number:4.2.1.142

MSA:

4.2.1.142;
Phylogenetic Tree:

4.2.1.142;
Uniprot:
M-CSA:
RHEA:35671 (S)-5'-oxoaverantin + H(+) = (1'S,5'S)-averufin + H2O
RULE(radius=1) ([*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]:[c;H0;+0:6](-[OH;+0:7]):[*:8]-[*:9]-[OH;+0:10]).[H+;H0:11]>>[*:5]:[c;H0;+0:6]1:[*:8]-[*:9]-[O;H0;+0:10]-[C;H0;+0:2](-[*:1])(-[*:3])-[O;H0;+0:4]-1.[OH2;+0:7]
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References

TitleAuthorsDatePubMed ID
Aspergillus parasiticus cyclase catalyzes two dehydration steps in aflatoxin biosynthesis.Sakuno E, Wen Y, Hatabayashi H, Arai H, Aoki C, Yabe K, Nakajima H2005 Jun15932995
Involvement of two cytosolic enzymes and a novel intermediate, 5'-oxoaverantin, in the pathway from 5'-hydroxyaverantin to averufin in aflatoxin biosynthesis.Sakuno E, Yabe K, Nakajima H2003 Nov14602595