EC number:4.2.1.148

Enzyme

Download
EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.148
Description:2-methylfumaryl-CoA hydratase.
Alternative Name: Mesaconyl-coenzyme A hydratase.
Mesaconyl-C(1)-CoA hydratase.
Erythro-beta-methylmalonyl-CoA hydrolyase.
Cath: 3.10.129.10;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.148
BRENDA Enzyme Link: BRENDA 4.2.1.148
KEGG Enzyme Link: KEGG4.2.1.148
BioCyc Enzyme Link: BioCyc 4.2.1.148
ExPASy Enzyme Link: ExPASy4.2.1.148
EC2PDB Enzyme Link: EC2PDB 4.2.1.148
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.148
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.148
IntEnz Enzyme Link: IntEnz 4.2.1.148
MEDLINE Enzyme Link: MEDLINE 4.2.1.148

EC number:4.2.1.148

MSA:

4.2.1.148;
Phylogenetic Tree:

4.2.1.148;
Uniprot:
M-CSA:
RHEA:38263 (2R,3S)-beta-methylmalyl-CoA = 2-methylfumaryl-CoA + H2O
RULE(radius=1) [*:1]-[CH;+0:2](-[OH;+0:3])-[CH;+0:4](-[*:5])-[*:6]>>[*:1]-[CH;+0:2]=[C;H0;+0:4](-[*:5])-[*:6].[OH2;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.Zarzycki J, Schlichting A, Strychalsky N, Müller M, Alber BE, Fuchs G2008 Feb18065535