EC number:4.2.1.150

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.150
Description:Short-chain-enoyl-CoA hydratase.
Alternative Name: Crotonase.
3-hydroxybutyryl-CoA dehydratase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.150
BRENDA Enzyme Link: BRENDA 4.2.1.150
KEGG Enzyme Link: KEGG4.2.1.150
BioCyc Enzyme Link: BioCyc 4.2.1.150
ExPASy Enzyme Link: ExPASy4.2.1.150
EC2PDB Enzyme Link: EC2PDB 4.2.1.150
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.150
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.150
IntEnz Enzyme Link: IntEnz 4.2.1.150
MEDLINE Enzyme Link: MEDLINE 4.2.1.150

EC number:4.2.1.150

MSA:

4.2.1.150;
Phylogenetic Tree:

4.2.1.150;
Uniprot:
M-CSA:
RHEA:52664 a short-chain (3S)-hydroxyacyl-CoA = a short-chain (2E)-enoyl-CoA + H2O
RULE(radius=1) [*:1]-[CH;+0:2](-[OH;+0:3])-[CH2;+0:4]-[*:5]>>[*:1]-[CH;+0:2]=[CH;+0:4]-[*:5].[OH2;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Purification and characterization of crotonase from Clostridium acetobutylicum.Waterson RM, Castellino FJ, Hass GM, Hill RL1972 Aug 255057466
Clinical, biochemical and metabolic characterisation of a mild form of human short-chain enoyl-CoA hydratase deficiency: significance of increased N-acetyl-S-(2-carboxypropyl)cysteine excretion.Yamada K, Aiba K, Kitaura Y, Kondo Y, Nomura N, Nakamura Y, Fukushi D, Murayama K, Shimomura Y, Pitt J, Yamaguchi S, Yokochi K, Wakamatsu N2015 Oct26251176