EC number:4.2.1.155

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.155
Description:Methylthioacryloyl-CoA hydratase.
Cath: 1.10.12.10; 3.90.226.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.155
BRENDA Enzyme Link: BRENDA 4.2.1.155
KEGG Enzyme Link: KEGG4.2.1.155
BioCyc Enzyme Link: BioCyc 4.2.1.155
ExPASy Enzyme Link: ExPASy4.2.1.155
EC2PDB Enzyme Link: EC2PDB 4.2.1.155
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.155
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.155
IntEnz Enzyme Link: IntEnz 4.2.1.155
MEDLINE Enzyme Link: MEDLINE 4.2.1.155

EC number:4.2.1.155

MSA:

4.2.1.155;
Phylogenetic Tree:

4.2.1.155;
Uniprot:
M-CSA:
RHEA:45144 3-(methylsulfanyl)acryloyl-CoA + 2 H2O = acetaldehyde + CO2 + CoA + methanethiol
RULE(radius=1) [*:1]=[C;H0;+0:2](-[CH;+0:3]=[CH;+0:4]-[S;H0;+0:5]-[*:6])-[S;H0;+0:7]-[*:8].[OH2;+0:9].[OH2;+0:10]>>[*:8]-[SH;+0:7].[*:6]-[SH;+0:5].[*:1]=[CH;+0:2]-[CH3;+0:3].[O;H0;+0:9]=[C;H0;+0:4]=[O;H0;+0:10]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Crystal structure of DmdD, a crotonase superfamily enzyme that catalyzes the hydration and hydrolysis of methylthioacryloyl-CoA.Tan D, Crabb WM, Whitman WB, Tong L201323704947
Novel pathway for assimilation of dimethylsulphoniopropionate widespread in marine bacteria.Reisch CR, Stoudemayer MJ, Varaljay VA, Amster IJ, Moran MA, Whitman WB2011 May 1221562561