EC number:4.2.1.159
| ID: | 4.2.1.159 |
|---|---|
| Description: | dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase. |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 4.2.1.159 |
| BRENDA Enzyme Link: | BRENDA 4.2.1.159 |
| KEGG Enzyme Link: | KEGG4.2.1.159 |
| BioCyc Enzyme Link: | BioCyc 4.2.1.159 |
| ExPASy Enzyme Link: | ExPASy4.2.1.159 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.1.159 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.1.159 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.1.159 |
| IntEnz Enzyme Link: | IntEnz 4.2.1.159 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.1.159 |
EC number:4.2.1.159
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:47972 | dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + H2O |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[OH;+0:3])-[CH;+0:4](-[*:5])-[OH;+0:6]>>[*:1]-[CH2;+0:2]-[C;H0;+0:4](-[*:5])=[O;H0;+0:6].[OH2;+0:3] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| TDP-L-megosamine biosynthesis pathway elucidation and megalomicin a production in Escherichia coli. | Useglio M, Peirú S, Rodríguez E, Labadie GR, Carney JR, Gramajo H | 2010 Jun | 20418422 |
| In vitro characterization of the enzymes involved in TDP-D-forosamine biosynthesis in the spinosyn pathway of Saccharopolyspora spinosa. | Hong L, Zhao Z, Melançon CE 3rd, Zhang H, Liu HW | 2008 Apr 9 | 18345667 |
| Biosynthesis of the dideoxysugar component of jadomycin B: genes in the jad cluster of Streptomyces venezuelae ISP5230 for L-digitoxose assembly and transfer to the angucycline aglycone. | Wang L, White RL, Vining LC | 2002 Apr | 11932454 |
| The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties. | González A, Remsing LL, Lombó F, Fernández MJ, Prado L, Braña AF, Künzel E, Rohr J, Méndez C, Salas JA | 2001 Feb | 11254130 |
| Deoxysugars in glycopeptide antibiotics: enzymatic synthesis of TDP-L-epivancosamine in chloroeremomycin biosynthesis. | Chen H, Thomas MG, Hubbard BK, Losey HC, Walsh CT, Burkart MD | 2000 Oct 24 | 11035791 |
| Identification and expression of genes involved in biosynthesis of L-oleandrose and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticus. | Aguirrezabalaga I, Olano C, Allende N, Rodriguez L, Braña AF, Méndez C, Salas JA | 2000 May | 10770761 |