Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.18
Description:Methylglutaconyl-CoA hydratase.
Prosite: PDOC00150;
PDB:
PDBScop
Cath: 1.10.12.10; 3.90.226.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.18
BRENDA Enzyme Link: BRENDA 4.2.1.18
KEGG Enzyme Link: KEGG4.2.1.18
BioCyc Enzyme Link: BioCyc 4.2.1.18
ExPASy Enzyme Link: ExPASy4.2.1.18
EC2PDB Enzyme Link: EC2PDB 4.2.1.18
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.18
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.18
IntEnz Enzyme Link: IntEnz 4.2.1.18
MEDLINE Enzyme Link: MEDLINE 4.2.1.18
MSA:

4.2.1.18;

Phylogenetic Tree:

4.2.1.18;

Uniprot:
M-CSA:
RHEA:21536 (3S)-hydroxy-3-methylglutaryl-CoA = H2O + trans-3-methylglutaconyl-CoA
RULE(radius=1) [*:1]-[CH2;+0:2]-[C;H0;+0:3](-[*:4])(-[*:5])-[OH;+0:6]>>[*:1]-[CH;+0:2]=[C;H0;+0:3](-[*:4])-[*:5].[OH2;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Enoyl-CoA hydratase. reaction, mechanism, and inhibition.Agnihotri G, Liu HW2003 Jan 212467702