EC number:4.2.1.19
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.2.1.19 |
| BRENDA Enzyme Link: | BRENDA 4.2.1.19 |
| KEGG Enzyme Link: | KEGG4.2.1.19 |
| BioCyc Enzyme Link: | BioCyc 4.2.1.19 |
| ExPASy Enzyme Link: | ExPASy4.2.1.19 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.1.19 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.1.19 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.1.19 |
| IntEnz Enzyme Link: | IntEnz 4.2.1.19 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.1.19 |
| RHEA:11040 | D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[OH;+0:3])-[CH;+0:4](-[*:5])-[OH;+0:6]>>[*:1]-[CH2;+0:2]-[C;H0;+0:4](-[*:5])=[O;H0;+0:6].[OH2;+0:3] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Isolation and characterization of cDNAs encoding imidazoleglycerolphosphate dehydratase from Arabidopsis thaliana. | Tada S, Volrath S, Guyer D, Scheidegger A, Ryals J, Ohta D, Ward E | 1994 Jun | 8066131 |
| Cloning, sequence analysis and expression of the gene encoding imidazole glycerol phosphate dehydratase in Cryptococcus neoformans. | Parker AR, Moore TD, Edman JC, Schwab JM, Davisson VJ | 1994 Jul 22 | 8045413 |
| Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination. | Bisson C, Britton KL, Sedelnikova SE, Rodgers HF, Eadsforth TC, Viner RC, Hawkes TR, Baker PJ, Rice DW | 2015 Jul 7 | 26095028 |
| The biosynthesis of histidine; D-erythro-imidazoleglycerol phosphate dehydrase. | AMES BN | 1957 Sep | 13475302 |
| Bisubstrate specificity in histidine/tryptophan biosynthesis isomerase from Mycobacterium tuberculosis by active site metamorphosis. | Due AV, Kuper J, Geerlof A, von Kries JP, Wilmanns M | 2011 Mar 1 | 21321225 |
| Structural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathway. | Rangarajan ES, Proteau A, Wagner J, Hung MN, Matte A, Cygler M | 2006 Dec 8 | 16966333 |