EC number:4.2.1.24

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.24
Description:Porphobilinogen synthase.
Alternative Name: Delta-aminolevulinic acid dehydratase.
Aminolevulinate dehydratase.
Prosite: PDOC00153;
PDB:
PDBScop
1L6Y 8028737; 8041116; 8028737; 8041116;
1L6S 8028737; 8041116; 8028737; 8041116;
1I8J 8028737; 8041116; 8028737; 8041116;
5MHB 8028737; 8041116;
1B4E 8028737; 8041116;
 » show all
Cath: 3.20.20.70;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.24
BRENDA Enzyme Link: BRENDA 4.2.1.24
KEGG Enzyme Link: KEGG4.2.1.24
BioCyc Enzyme Link: BioCyc 4.2.1.24
ExPASy Enzyme Link: ExPASy4.2.1.24
EC2PDB Enzyme Link: EC2PDB 4.2.1.24
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.24
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.24
IntEnz Enzyme Link: IntEnz 4.2.1.24
MEDLINE Enzyme Link: MEDLINE 4.2.1.24

EC number:4.2.1.24

MSA:

4.2.1.24;
Phylogenetic Tree:

4.2.1.24;
Uniprot:
M-CSA:
RHEA:24064 2 5-aminolevulinate = H(+) + 2 H2O + porphobilinogen
RULE(radius=1) [*:1]-[C;H0;+0:2](=[O;H0;+0:3])-[CH2;+0:4]-[NH2;+0:5].[*:6]-[CH2;+0:7]-[C;H0;+0:8](-[*:9])=[O;H0;+0:10]>>[*:1]-[c;H0;+0:2]1:[cH;+0:4]:[nH;+0:5]:[c;H0;+0:8](-[*:9]):[c;H0;+0:7]:1-[*:6].[OH2;+0:10].[OH2;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction