Enzyme

Download
EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.30
Description:Glycerol dehydratase.
Cath: 1.10.1510.20; 3.20.20.350; 3.30.420.40; 3.50.30.70; 3.90.470.30; 2.40.50.140; 3.40.50.10150;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.30
BRENDA Enzyme Link: BRENDA 4.2.1.30
KEGG Enzyme Link: KEGG4.2.1.30
BioCyc Enzyme Link: BioCyc 4.2.1.30
ExPASy Enzyme Link: ExPASy4.2.1.30
EC2PDB Enzyme Link: EC2PDB 4.2.1.30
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.30
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.30
IntEnz Enzyme Link: IntEnz 4.2.1.30
MEDLINE Enzyme Link: MEDLINE 4.2.1.30
MSA:

4.2.1.30;

Phylogenetic Tree:

4.2.1.30;

Uniprot:
M-CSA:
RHEA:19765 glycerol = 3-hydroxypropanal + H2O
RULE(radius=1) [*:1]-[CH;+0:2](-[OH;+0:3])-[CH2;+0:4]-[OH;+0:5]>>[*:1]-[CH2;+0:2]-[CH;+0:4]=[O;H0;+0:5].[OH2;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Enhancement of pH stability and activity of glycerol dehydratase from Klebsiella pneumoniae by rational design.Qi X, Guo Q, Wei Y, Xu H, Huang R2012 Feb22042303
Insight into the mechanism of the B12-independent glycerol dehydratase from Clostridium butyricum: preliminary biochemical and structural characterization.O'Brien JR, Raynaud C, Croux C, Girbal L, Soucaille P, Lanzilotta WN2004 Apr 2715096031
Glycerol fermentation in Klebsiella pneumoniae: functions of the coenzyme B12-dependent glycerol and diol dehydratases.Forage RG, Foster MA1982 Feb7035429