EC number:4.2.1.35

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.35
Description:(R)-2-methylmalate dehydratase.
Alternative Name: Citraconate hydratase.
Cath: 3.20.19.10; 3.30.499.10; 3.30.499.20;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.35
BRENDA Enzyme Link: BRENDA 4.2.1.35
KEGG Enzyme Link: KEGG4.2.1.35
BioCyc Enzyme Link: BioCyc 4.2.1.35
ExPASy Enzyme Link: ExPASy4.2.1.35
EC2PDB Enzyme Link: EC2PDB 4.2.1.35
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.35
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.35
IntEnz Enzyme Link: IntEnz 4.2.1.35
MEDLINE Enzyme Link: MEDLINE 4.2.1.35

EC number:4.2.1.35

MSA:

4.2.1.35;
Phylogenetic Tree:

4.2.1.35;
Uniprot:
M-CSA:
RHEA:42424 2-methylmaleate + H2O = (2R,3S)-3-methylmalate
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[CH;+0:4](-[*:5])-[OH;+0:6]>>[*:1]-[C;H0;+0:2](-[*:3])=[CH;+0:4]-[*:5].[OH2;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Enzymology and evolution of the pyruvate pathway to 2-oxobutyrate in Methanocaldococcus jannaschii.Drevland RM, Waheed A, Graham DE2007 Jun17449626
RHEA:22332 (3R)-citramalate = 2-methylmaleate + H2O
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3])(-[OH;+0:4])-[CH2;+0:5]-[*:6]>>[*:1]-[C;H0;+0:2](-[*:3])=[CH;+0:5]-[*:6].[OH2;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Enzymology and evolution of the pyruvate pathway to 2-oxobutyrate in Methanocaldococcus jannaschii.Drevland RM, Waheed A, Graham DE2007 Jun17449626