EC number:4.2.1.36
| ID: | 4.2.1.36 | ||
|---|---|---|---|
| Description: | Homoaconitate hydratase. | ||
| Alternative Name: |
Homoaconitase. HACN. Cis-homoaconitase. 2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase. | ||
| Prosite: | PDOC00423; | ||
| PDB: |
|
||
| Cath: | 1.10.238.260; 1.10.287.40; 1.10.287.4050; 3.20.19.10; 3.20.20.70; 3.30.499.10; 3.30.499.20; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.2.1.36 |
| BRENDA Enzyme Link: | BRENDA 4.2.1.36 |
| KEGG Enzyme Link: | KEGG4.2.1.36 |
| BioCyc Enzyme Link: | BioCyc 4.2.1.36 |
| ExPASy Enzyme Link: | ExPASy4.2.1.36 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.1.36 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.1.36 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.1.36 |
| IntEnz Enzyme Link: | IntEnz 4.2.1.36 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.1.36 |
| RHEA:15485 | (1R,2S)-homoisocitrate = cis-homoaconitate + H2O |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[OH;+0:3])-[CH;+0:4](-[*:5])-[*:6]>>[*:1]-[CH;+0:2]=[C;H0;+0:4](-[*:5])-[*:6].[OH2;+0:3] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Methanogen homoaconitase catalyzes both hydrolyase reactions in coenzyme B biosynthesis. | Drevland RM, Jia Y, Palmer DR, Graham DE | 2008 Oct 24 | 18765671 |