Enzyme

Download
EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.41
Description:5-dehydro-4-deoxyglucarate dehydratase.
Alternative Name: D-4-deoxy-5-ketoglucarate hydro-lyase.
5-keto-4-deoxy-glucarate dehydratase.
Cath: 3.20.20.70;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.41
BRENDA Enzyme Link: BRENDA 4.2.1.41
KEGG Enzyme Link: KEGG4.2.1.41
BioCyc Enzyme Link: BioCyc 4.2.1.41
ExPASy Enzyme Link: ExPASy4.2.1.41
EC2PDB Enzyme Link: EC2PDB 4.2.1.41
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.41
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.41
IntEnz Enzyme Link: IntEnz 4.2.1.41
MEDLINE Enzyme Link: MEDLINE 4.2.1.41
MSA:

4.2.1.41;

Phylogenetic Tree:

4.2.1.41;

Uniprot:
M-CSA:
RHEA:24608 5-dehydro-4-deoxy-D-glucarate + H(+) = 2,5-dioxopentanoate + CO2 + H2O
RULE(radius=1) [*:1]=[C;H0;+0:2](-[OH;+0:3])-[CH;+0:4](-[OH;+0:5])-[CH;+0:6](-[*:7])-[OH;+0:8].[H+;H0:9]>>[*:7]-[CH2;+0:6]-[CH;+0:4]=[O;H0;+0:5].[*:1]=[C;H0;+0:2]=[O;H0;+0:3].[OH2;+0:8]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
New insights into the alternative D-glucarate degradation pathway.Aghaie A, Lechaplais C, Sirven P, Tricot S, Besnard-Gonnet M, Muselet D, de Berardinis V, Kreimeyer A, Gyapay G, Salanoubat M, Perret A2008 Jun 618364348