EC number:4.2.1.42
| ID: | 4.2.1.42 |
|---|---|
| Description: | Galactarate dehydratase. |
| Alternative Name: |
D-galactarate hydro-lyase. |
| Cath: | 3.20.20.120; 3.30.390.10; 3.90.1210.30; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.2.1.42 |
| BRENDA Enzyme Link: | BRENDA 4.2.1.42 |
| KEGG Enzyme Link: | KEGG4.2.1.42 |
| BioCyc Enzyme Link: | BioCyc 4.2.1.42 |
| ExPASy Enzyme Link: | ExPASy4.2.1.42 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.1.42 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.1.42 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.1.42 |
| IntEnz Enzyme Link: | IntEnz 4.2.1.42 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.1.42 |
| RHEA:16005 | galactarate = 5-dehydro-4-deoxy-D-glucarate + H2O |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[OH;+0:3])-[CH;+0:4](-[*:5])-[OH;+0:6]>>[*:1]-[C;H0;+0:2](=[O;H0;+0:3])-[CH2;+0:4]-[*:5].[OH2;+0:6] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli. | Hubbard BK, Koch M, Palmer DR, Babbitt PC, Gerlt JA | 1998 Oct 13 | 9772162 |
| Computation-facilitated assignment of the function in the enolase superfamily: a regiochemically distinct galactarate dehydratase from Oceanobacillus iheyensis . | Rakus JF, Kalyanaraman C, Fedorov AA, Fedorov EV, Mills-Groninger FP, Toro R, Bonanno J, Bain K, Sauder JM, Burley SK, Almo SC, Jacobson MP, Gerlt JA | 2009 Dec 8 | 19883118 |
| Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2. | Yew WS, Fedorov AA, Fedorov EV, Almo SC, Gerlt JA | 2007 Aug 21 | 17649980 |