Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.45
Description:CDP-glucose 4,6-dehydratase.
Cath: 3.40.50.720; 3.90.25.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.45
BRENDA Enzyme Link: BRENDA 4.2.1.45
KEGG Enzyme Link: KEGG4.2.1.45
BioCyc Enzyme Link: BioCyc 4.2.1.45
ExPASy Enzyme Link: ExPASy4.2.1.45
EC2PDB Enzyme Link: EC2PDB 4.2.1.45
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.45
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.45
IntEnz Enzyme Link: IntEnz 4.2.1.45
MEDLINE Enzyme Link: MEDLINE 4.2.1.45
MSA:

4.2.1.45;

Phylogenetic Tree:

4.2.1.45;

Uniprot:
M-CSA:
RHEA:17153 CDP-D-glucose = CDP-4-dehydro-6-deoxy-D-glucose + H2O
RULE(radius=1) [*:1]-[CH;+0:2](-[OH;+0:3])-[*:4]-[CH2;+0:5]-[OH;+0:6]>>[*:1]-[C;H0;+0:2](=[O;H0;+0:3])-[*:4]-[CH3;+0:5].[OH2;+0:6]
Reaction
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References

TitleAuthorsDatePubMed ID
Structure of CDP-D-glucose 4,6-dehydratase from Salmonella typhi complexed with CDP-D-xylose.Koropatkin NM, Holden HM2005 Apr15805590
Crystal structure at 1.8 A resolution of CDP-D-glucose 4,6-dehydratase from Yersinia pseudotuberculosis.Vogan EM, Bellamacina C, He X, Liu HW, Ringe D, Petsko GA2004 Mar 2315023057