Enzyme

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     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.49
Description:Urocanate hydratase.
Alternative Name: Urocanase.
Imidazolonepropionate hydrolase.
Prosite: PDOC00947;
PDB:
PDBScop
2FKN 8079164; 8079165; 8091451; 8079164; 8079165; 8091451; 8079164; 8079165; 8091451; 8079164; 8079165; 8091451;
2V7G 8003578; 8003579; 8091450; 8003578; 8003579; 8091450; 8003578; 8003579; 8091450; 8003578; 8003579; 8091450;
1UWL 8003578; 8003579; 8091450; 8003578; 8003579; 8091450;
Cath: 3.40.1770.10; 3.40.50.10730;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.49
BRENDA Enzyme Link: BRENDA 4.2.1.49
KEGG Enzyme Link: KEGG4.2.1.49
BioCyc Enzyme Link: BioCyc 4.2.1.49
ExPASy Enzyme Link: ExPASy4.2.1.49
EC2PDB Enzyme Link: EC2PDB 4.2.1.49
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.49
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.49
IntEnz Enzyme Link: IntEnz 4.2.1.49
MEDLINE Enzyme Link: MEDLINE 4.2.1.49
MSA:

4.2.1.49;

Phylogenetic Tree:

4.2.1.49;

Uniprot:
M-CSA:
RHEA:13101 4-imidazolone-5-propanoate = H2O + trans-urocanate
RULE(radius=1)
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Structure and action of urocanase.Kessler D, Rétey J, Schulz GE2004 Sep 315313616