EC number:4.2.1.56

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.56
Description:Itaconyl-CoA hydratase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.56
BRENDA Enzyme Link: BRENDA 4.2.1.56
KEGG Enzyme Link: KEGG4.2.1.56
BioCyc Enzyme Link: BioCyc 4.2.1.56
ExPASy Enzyme Link: ExPASy4.2.1.56
EC2PDB Enzyme Link: EC2PDB 4.2.1.56
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.56
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.56
IntEnz Enzyme Link: IntEnz 4.2.1.56
MEDLINE Enzyme Link: MEDLINE 4.2.1.56

EC number:4.2.1.56

MSA:

4.2.1.56;
Phylogenetic Tree:

4.2.1.56;
Uniprot:
M-CSA:
RHEA:13785 citramalyl-CoA = H2O + itaconyl-CoA
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3])(-[CH3;+0:4])-[OH;+0:5]>>[*:1]-[C;H0;+0:2](-[*:3])=[CH2;+0:4].[OH2;+0:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The Human Knockout Gene CLYBL Connects Itaconate to Vitamin B<sub>12</sub>.Shen H, Campanello GC, Flicker D, Grabarek Z, Hu J, Luo C, Banerjee R, Mootha VK2017 Nov 229056341
The pathway of itaconate metabolism by liver mitochondria.WANG SF, ADLER J, LARDY HA1961 Jan13783048