EC number:4.2.1.59
| ID: | 4.2.1.59 |
|---|---|
| Description: | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase. |
| Alternative Name: |
D-3-hydroxyoctanoyl-[acyl carrier protein] dehydratase. Beta-hydroxyoctanoyl-acyl carrier protein dehydrase. Beta-hydroxyoctanoyl-ACP-dehydrase. Beta-hydroxyoctanoyl thioester dehydratase. 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase. (3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] hydro-lyase. |
| Cath: | 1.10.110.40; 1.10.1200.10; 1.10.1470.20; 1.10.287.1960; 1.10.287.3140; 1.10.287.3150; 1.20.1050.120; 1.20.5.3540; 1.20.5.3640; 3.20.20.70; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.2.1.59 |
| BRENDA Enzyme Link: | BRENDA 4.2.1.59 |
| KEGG Enzyme Link: | KEGG4.2.1.59 |
| BioCyc Enzyme Link: | BioCyc 4.2.1.59 |
| ExPASy Enzyme Link: | ExPASy4.2.1.59 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.1.59 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.1.59 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.1.59 |
| IntEnz Enzyme Link: | IntEnz 4.2.1.59 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.1.59 |
| RHEA:13097 | a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[CH;+0:3](-[*:4])-[OH;+0:5]>>[*:1]-[CH;+0:2]=[CH;+0:3]-[*:4].[OH2;+0:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Roles of the FabA and FabZ beta-hydroxyacyl-acyl carrier protein dehydratases in Escherichia coli fatty acid biosynthesis. | Heath RJ, Rock CO | 1996 Nov 1 | 8910376 |
| Crystallization and preliminary X-ray analysis of beta-hydroxydecanoyl thiol ester dehydrase from Escherichia coli. | Sharma A, Henderson BS, Schwab JM, Smith JL | 1990 Mar 25 | 2180957 |
| An ancient genetic link between vertebrate mitochondrial fatty acid synthesis and RNA processing. | Autio KJ, Kastaniotis AJ, Pospiech H, Miinalainen IJ, Schonauer MS, Dieckmann CL, Hiltunen JK | 2008 Feb | 17898086 |
| Fatty acid synthesis and elongation in yeast. | Tehlivets O, Scheuringer K, Kohlwein SD | 2007 Mar | 16950653 |