Enzyme

Download
EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.66
Description:Cyanide hydratase.
Alternative Name: Formamide hydro-lyase.
Prosite: PDOC50263; PDOC00712;
PDB:
PDBScop

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.66
BRENDA Enzyme Link: BRENDA 4.2.1.66
KEGG Enzyme Link: KEGG4.2.1.66
BioCyc Enzyme Link: BioCyc 4.2.1.66
ExPASy Enzyme Link: ExPASy4.2.1.66
EC2PDB Enzyme Link: EC2PDB 4.2.1.66
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.66
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.66
IntEnz Enzyme Link: IntEnz 4.2.1.66
MEDLINE Enzyme Link: MEDLINE 4.2.1.66
MSA:

4.2.1.66;

Phylogenetic Tree:

4.2.1.66;

Uniprot:
M-CSA:
RHEA:21720 formamide = H2O + hydrogen cyanide
RULE(radius=1) [NH2;+0:1]-[CH;+0:2]=[O;H0;+0:3]>>[CH;+0:2]#[N;H0;+0:1].[OH2;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
A comparative study of nitrilases identified by genome mining.Kaplan O, Veselá AB, Petříčková A, Pasquarelli F, Pičmanová M, Rinágelová A, Bhalla TC, Pátek M, Martínková L2013 Jul23475593
Cyanide degradion by an enzyme from Stemphylium loti.Fry WE, Millar RL1972 Aug5065258
Purification and characterization of cyanide hydratase from the phytopathogenic fungus Gloeocercospora sorghi.Wang P, Matthews DE, VanEtten HD1992 Nov 11416986